Differentiation of human stem cells to endpoint cell types (CANADA RESEARCH CHAIRHOLDER)

Scott Brown

Interrogating large-scale cancer genome datasets to aid in the development of personalized cancer immunotherapies.

All cancers but non-melanoma skin cancer Melanoma of skin

Alan Anderson

Inducible metabolism of xenochemicals and endogenous toxic compounds: Nuclear receptors and the CYP2B paradigm

All cancers but non-melanoma skin cancer Melanoma of skin

Ira Pastan

Immunotoxin Therapy of Solid and Hematopoietic Tumors: Preclinical Studies

All cancers but non-melanoma skin cancer

Pathology Hematology and hematologic malignancies

A. K. M. Nur-Ur Rahman

Defining the role of T cell metabolism in HIV-induced chronic immune activation and immune dysfunction.

Melanoma of skin All cancers but non-melanoma skin cancer

Daniel Durocher

Understanding DNA damage signaling by the ubiquitin ligases RNF8 and RNF168

All cancers but non-melanoma skin cancer Melanoma of skin

Peter Blumberg

Molecular Mechanism of Action of Phorbol Ester

Melanoma of skin All cancers but non-melanoma skin cancer

Alexander Palazzo

Dissecting the Molecular Mechanisms of the Alternative Nuclear Export and Endoplasmic Reticulum Targeting of Secretory mRNAs.

All cancers but non-melanoma skin cancer Melanoma of skin

Pathology

Charles D Allis

Oncohistones: Role of Histone H3 Mutations in the Oncogenesis of Pediatric Cancers

All cancers but non-melanoma skin cancer

Pediatric oncology or childhood cancer

Marco Marra

Exploring the relationship between the genome and the epigenome in cancers

All cancers but non-melanoma skin cancer Melanoma of skin