CRC Tier 1 - Determining why mutations of the metabolic enzyme isocitrate dehydrogenase cause leukemias and brain cancers

Terry Fry

ALL Immunobiology and the Bone Marrow Niche

Leukaemia

Hematology and hematologic malignancies Pediatric oncology or childhood cancer

Peter Stirling

Mechanisms of genome instability induced by RNA splicing defects

Leukaemia

Peter Aplan

Collaborative Pathways that Lead to Leukemia – Rockville

Leukaemia

Pathology Hematology and hematologic malignancies

Michael R Green

Identification and Characterization of Genes that Suppress BCR-ABL+ Leukemia

Leukaemia

Hematology and hematologic malignancies Pathology

Xiaoyan Jiang

Molecular Targeting of Critical Domains of AHI-1 Oncoprotein in Chronic Myeloid Leukemia Stem Cells Resistant to Current Tyrosine Kinase Inhibitor Therapy

Leukaemia

Peter Aplan

Collaborative Pathways that Lead to Leukemia

Leukaemia

Pathology Hematology and hematologic malignancies

Giovanna Tosato

Study of the Roles of SDF1 and CXCR4 in Hematopoiesis

Leukaemia

Hematology and hematologic malignancies

Charles D Allis

Oncohistones: Role of Histone H3 Mutations in the Oncogenesis of Pediatric Cancers

Brain, nervous system

Pediatric oncology or childhood cancer

H Leighton Grimes

Developing Novel STAT5 Protein Inhibitors for Treatment of Leukemias

Leukaemia

Hematology and hematologic malignancies Pathology