Map - The GO Map

Projects

1962

Project leads

1598

Collaborators

1595

William J Murphy

1 of 3 Interdisciplinary Collaboratory for Enhancing Translational Therapeutics Utilizing Biologically, Immunologically, and Metabollically Relevant Models of Breast Cancer

Robert J Turesky

2-Amino-9H-pyrido[2,3-b]indole: a Potential Colorectal Carcinogen Formed in Tobac

Matthew L Freedman

4C and Genome Editing for Causal SNP and Gene Discovery at Cancer Risk Loci

Melanoma of skin All cancers but non-melanoma skin cancer

Shridar Ganesan

53BP1-Mediated Regulation of DNA Repair and Chemoresistance

Gerd P Pfeifer

5-hydroxymethylcytosine in Human Cancer

Leukaemia Brain, nervous system

Daniela Salvemini

A3AR Agonists to Prevent Chemotherapy-Induced Painful Peripheral Neuropathy

All cancers but non-melanoma skin cancer

Alex Kentsis

Aberrant activation of HGF/MET signaling as a therapeutic target in AML

Zhihong Gong

Aberrant DNA methylation patterns of miRNAs and breast cancer racial disparities

Elizabeth Grimm

Aberrant Silencing of a Large Micro-RNA Cluster on Chromosome 14q32 and its Relation to Aberrant c-MET/n-RAS Signaling in Cutaneous Malignant Melanoma-Implications for Novel Therapeutic Approaches and Biomarkers

Melanoma of skin

Anna R. Giuliano

A Biomarker-related Approach to Screening for HPV-related Oropharyngeal Cancer

Oesophagus Lip, oral cavity

Ninh La-Beck

Abrogating Nanoparticle-induced Immunosuppression in Tumor Microenvironment

All cancers but non-melanoma skin cancer

Alastair Davies

A Cancer Stem Cell-Directed Therapy for Enzalutamide-Resistant Prostate Cancer

Surgery / Surgical oncology

Shuji Ogino

Accelerating Transdisciplinary Epidemiology of Colorectal Cancer

John Bligh

Accelerating translational research through Cardiff University's Clinical Innovation pipeline

Melanoma of skin All cancers but non-melanoma skin cancer

Lingyin Li

A chemical biology approach towards understanding the anti-cancer innate immunity

All cancers but non-melanoma skin cancer

David E Goldgar

A Comprehensive Approach to Breast Cancer Susceptibility Across the Risk Spectrum

Christian Landry

A comprehensive genotype-phenotype map of a eukaryotic complexome

Melanoma of skin All cancers but non-melanoma skin cancer

Hisataka Kobayashi

Activatable Molecular Cancer Imaging Probe

All cancers but non-melanoma skin cancer

Peter Aplan

Activation of Proto-Oncogenes by Chromosomal Translocation

Hematology and hematologic malignancies Pathology

Barbara H Jung

Activin Signaling and Regulation in the Colon

Kinam Park

Adaptable Polymer Micelles for Tumor Targeting

Prostate Breast

Sheena N Smith

Adenoviral delivery of protein-based therapeutics to the tumor microenvironment

Dmitry Temiakov

Administrative Supplement for R01 GM104231-01 Mechanisms of transcription initiation in mitochondria

Melanoma of skin All cancers but non-melanoma skin cancer

Terry Fry

Adoptive T cell Therapy for Pediatric Leukemia

Pediatric oncology or childhood cancer

Erica K Sloan

Adrenergic Regulation of Tumor Inflammation and Metastatic Dissemination

Amanda G Paulovich

Advanced development of immuno-MRM technology to analyze archived cancer tissues

Melanoma of skin All cancers but non-melanoma skin cancer

Stephan Maier

Advanced Techniques For Rapid And Artifact-Resistant MR Diffusion Imaging

Prostate Brain, nervous system

Dale Wigley

A facility for in-house analysis and X-ray data collection of crystals with large subunit cells.

Melanoma of skin All cancers but non-melanoma skin cancer

Radiation Oncology

Annalisa Carlucci

A Functional Genomic Screen of De-Ubiquitinating Enzymes Involved in Ovarian Cancer Progression

Eric Collisson

A Genetically Defined System to Identify Factors Essential for KRas Oncogenesis

Peter Roy

A Genetic and Biochemical Analysis of the Novel Guidance Cue MADD-4

Melanoma of skin All cancers but non-melanoma skin cancer

Sarah Hughes

A Genetic Model for Neurofibromatosis Type II

Melanoma of skin All cancers but non-melanoma skin cancer

Nicholas Schuh

A genetic regulatory model of interleukin-17-mediated gut inflammation and immunity.

Brian Raught

A Global Ubiquitin-Proteasome System Map

Melanoma of skin All cancers but non-melanoma skin cancer

Joseph Barchi

A Glycopeptide from Interstitial Cystitis Patients as a Novel Anticancer Lead

All cancers but non-melanoma skin cancer

Carl Hansen

A high-throughput single-cell technology for the function-based discovery of monoclonal antibody antagonists of G-protein coupled receptors in cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Casey Farquhar

AIDS International Training and Research Program

Kaposi sarcoma Colorectum Cervix uteri Brain, nervous system

Yuet Ming Rebecca Chin

Akt isoform-specific signaling in breast cancer metastasis

Jae H Kang

A Large Randomized Trial of Vitamin D, Omega-3 Fatty Acids and Cognitive Decline

Melanoma of skin All cancers but non-melanoma skin cancer

Shakti H Ramkissoon

ALK signaling in CNS development, ischemic brain injury and gliomagenesis

Brain, nervous system

Terry Fry

ALL Immunobiology and the Bone Marrow Niche

Hematology and hematologic malignancies Pediatric oncology or childhood cancer

Marie Bleakley

Allogeneic stem cell transplant with grafts depleted of naive T cells for leukemi

All cancers but non-melanoma skin cancer

Ronald S Rock

Allostery in myosins studied at the molecular level

All cancers but non-melanoma skin cancer

Valeri Vasioukhin

Alpha-Catenin in Regulation of Tissue Homeostasis and Cancer

Melanoma of skin All cancers but non-melanoma skin cancer

John Tavis

Alpha Hydroxytropolones as HCC Preventatives

Liver and intrahepatic bile ducts

Renato V Iozzo

Altered Proteoglycan Gene Expression and Cancer

Powel Brown

ALTERNATIVE DOSING OF EXEMESTANE IN POSTMENOPAUSAL WOMEN WITH STAGE 0-II ER-POSITIVE BREAST CANCER: A RANDOMIZED PRESURGICAL TRIAL

Vladimir Bogdanov

Alternatively Spliced Tissue Factor and Pathobiology of Pancreatic Cancer

Mikel Garcia-Marcos

Alternative mechanisms of signaling via trimeric G proteins

Melanoma of skin All cancers but non-melanoma skin cancer

Zhiyuan Shen

Alternative Mechanisms to Inactivate p53 during Oncogenesis

Non-Melanoma skin cancer Breast Brain, nervous system

Zhiyuan Shen

Alternative Mechanisms to Inactivate p53 During Oncogenesis

Non-Melanoma skin cancer Breast Brain, nervous system

Jan Rainey

A mechanistic study of G-protein coupled receptor binding and activation by apelin.

Trachea, bronchus and lung Other pharynx Oesophagus Non-Hodgkin lymphoma Nasopharynx Liver and intrahepatic bile ducts Kidney, renal pelvis and ureter Kaposi sarcoma Hodgkin lymphoma Colorectum Cervix uteri

Humsa Venkatesh

A Mechanistic Understanding of Neuronal Activity Promotion of High-Grade Glioma Growth through Activity-Regulated Secretion of Neuroligin-3

Brain, nervous system

Kathleen Kelly Siebenlist

A Mitogen-induced G Protein-coupled Receptor

Margaret A Goodell

A Mouse Model of DNMT3A-Associated Hematologic Malignancy

Non-Hodgkin lymphoma Leukaemia Hodgkin lymphoma

Scott Kopetz

AMPK Directs the Balance Between Mutant Kras and PI3K Signaling and Defines Molecular Subsets in Colorectal Cancer

Anna L Malkova

Amplification of risk resulting from mis-routing of double-strand break repair

All cancers but non-melanoma skin cancer

Powel Brown

A MULTICENTER PHASE II STUDY OF DOCOSAHEXAENOIC ACID IN PATIENTS WITH A HISTORY OF BREAST CANCER, PREMALIGNANT LESIONS, OR BENIGN BREAST DISEASE

Eric B. Haura

AN ACTIVE ROLE OF ADAPTOR PROTEINS IN TYROSINE KINASE INHIBITOR RESISTANCE

Trachea, bronchus and lung

Junjie Chen

Analysis of BRCA1 function in DNA Repair

Ralph Scully

Analysis of BRCA1 Recombination Functions

Tim Greten

Analysis of Cancer-Related Immune Suppressor Mechanisms in Mice

Carl D Novina

Analysis of cap-dependent translational repression by microRNAs in oncogenisis

Melanoma of skin All cancers but non-melanoma skin cancer

Yamini Dalal

Analysis of Centromere Identity and Structure in Human Cells

All cancers but non-melanoma skin cancer

Habtom Ressom

Analysis of Lc-MS Data to Identify Peptide and Glycan Biomarkers for Hepatocellular Carcinoma.

Liver and intrahepatic bile ducts

Charlotte Kuperwasser

Analysis of the cellular and molecular determinants of the human breast hierarchy

Antonio J Giraldez

Analysis of the gene networks regulating the maternal to zygotic transition

All cancers but non-melanoma skin cancer

Stephen J Elledge

Analysis of the Mammalian DNA Damage Response

Charles Roberts

Analysis of the role of the SWI/SNF complex in tumor suppression

Melanoma of skin All cancers but non-melanoma skin cancer

Richard Hodes

Analysis of the T Cell Repertoire

Radiation Oncology

John J. Krolewski

An Androgen-Regulated Cytokine Network Controls Prostate Apoptosis.

Richard L Haspel

A National Curriculum in Cancer Genomics for Pathology Residents

Melanoma of skin All cancers but non-melanoma skin cancer

Steven P. Balk

Androgen Receptor Action in Castration Resistant Prostate Cancer

Kevin Hughes Kensler

Androgen receptor expression and signaling and breast cancer risk and progression

Zijie Sun

A new regulator for Wnt/beta-catenin signaling and prostate tumorigenesis

Zijie Sun

A New Regulator for Wnt/beta-catenin Signaling and Prostate Tumorigenesis

Giovanna Tosato

Angiogenesis and Tumor Growth

Trachea, bronchus and lung Kaposi sarcoma

Peter Choyke

Angiogenesis Imaging

Breast Brain, nervous system

Paul J. Anderson

Angiogenin-Induced RNA Cleavage in Cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Oliver Smithies

Animal Models for Studying the Genetics of Hypertension

All cancers but non-melanoma skin cancer

Laura A Johnston

An innate system for detection of aberrant tissue growth

All cancers but non-melanoma skin cancer

Myron D Gross

An Integrated Study of Mitochondrial Pathways in Colorectal Cancer

Helen Tanton

An investigation into the role of ATPase Inhibitory Factor 1 in pancreatic cancer

All cancers but non-melanoma skin cancer

Richard J Gilbertson

An Investigation of Radial Glia as the Source of Ependymoma Stem Cells

Brain, nervous system

Sarit Smolikove

An organismal approach to dissecting the mechanism of DSB repair pathway choice

All cancers but non-melanoma skin cancer

Genaro R. Villa

A Novel Approach to Treating Glioblastoma through Activation of the Liver X Recep

Brain, nervous system

Nikolaos Parisis

A Novel Histone H3 Phosphorylation that Regulates Genome Integrity

All cancers but non-melanoma skin cancer

Maike Sander

A novel mouse model to identify biomarkers of IPMN formation and progression

Ankit Sinha

A novel N-glyco-proteomics driven strategy to identify tumour secreted proteins using patient-derived xenografts.

Lixin Wan

A Novel Oncogenic Role for Cdc20 Implications in Adult T Cell Leukemia Treatment

Barbara M Mueller

A Novel Plasminogen Receptor in Breast Cancer

Jenny Hsu

A novel role for E2F4 as a transcriptional activator and a cell cycle driver

Melanoma of skin All cancers but non-melanoma skin cancer

Prabodhika Mallikaratchy

Antibody Guided Cell-SELEX Technology

All cancers but non-melanoma skin cancer

James D Marks

Antibody Research Technology Center

Sarcoma Nasopharynx Kidney, renal pelvis and ureter All cancers but non-melanoma skin cancer

Dimiter Dimitrov

Antibody therapeutics against biodefense-related diseases

Brain, nervous system

Scott H Kaufmann

Anticancer Drug-Induced BH3-only Protein.Bak Interactions

Non-Hodgkin lymphoma

Hematology and hematologic malignancies Pathology

Brian A Cobb

Antigenic Carbohydrate Structure, Function, and Specificity

All cancers but non-melanoma skin cancer

Jay Berzofsky

Antigen-specific T-cell Activation, Application to Vaccines for Cancer and AIDS

Prostate Breast

John Digiovanni

Anti-Promoting Effects of Triterpenes Alone or Combined with Other Phytochemicals

Melanoma of skin Non-Melanoma skin cancer

Gary Rosenberg

AP 1. Biodiversity

Pancreas Brain, nervous system

Gisela P Concepcion

AP 3. Chemistry and Drug Discovery

Pancreas Brain, nervous system

Eric W Schmidt

AP 4. Drug Screening and Pharmacology

Pancreas Brain, nervous system

Gobel Verena

Apical membrane modeling in tubulogenesis

All cancers but non-melanoma skin cancer

Scott Atwood

aPKC function in Hedgehog signaling and basal cell carcinoma

All cancers but non-melanoma skin cancer

Richard K. Wilson

A Platform for Large-Scale Genomic Discovery

All cancers but non-melanoma skin cancer

Sharad Kumar

Apoptosomes Structure and Procaspase Activation

All cancers but non-melanoma skin cancer

Natalie Fox

A portrait of functional associations of DNA and RNA in prostate cancer

Robert A Gatenby

Application of Evolutionary Principles to Maintain Cancer Control (PQ21)

Paul L Fox

A protein-directed RNA switch that regulates translation

All cancers but non-melanoma skin cancer

Elliot Chaikof

A PSGL-1 Glycopeptide Mimetic for Treatment of Venous Thromboembolism

Melanoma of skin All cancers but non-melanoma skin cancer

Joseph H Antin

A Randomized Trial of Tac/MTX/bortezomib vs Tac/MTXplacebo in Allogeneic HSCT

Non-Hodgkin lymphoma Leukaemia Hodgkin lymphoma

David Fitch

Architecture of a Genetic Network Governing Morphogenesis

All cancers but non-melanoma skin cancer

Scott M Dehm

AR Gene Rearrangements and AR Signaling in Prostate Cancer

Jun J Yang

ARID5B and Disparities of Childhood Leukemia

Hematology and hematologic malignancies Pediatric oncology or childhood cancer

Giovanna Tosato

A Role for KSHV in the Pathogenesis of Malignancies

Trachea, bronchus and lung Kaposi sarcoma Hodgkin lymphoma

Hematology and hematologic malignancies Pathology

Myron Steve Ignatius

A role for notch in self renewal in embryonal rhabdomyosarcoma

Investigator from Spanish National Research Council

Artificial evolution of a novel multifunctional human polymerase

Melanoma of skin All cancers but non-melanoma skin cancer

Elaine Dunleavy

Assembly and function of Drosophila melanogaster centromeric chromatin during meiosis and development.

Melanoma of skin All cancers but non-melanoma skin cancer

William Muller

Assess the relative contribution of particular signaling molecules to each stage of breast cancer progression (CANADA RESEARCH CHAIRHOLDER)

Melanoma of skin All cancers but non-melanoma skin cancer

Jian-Yue Jin

A Synchronized Moving Grid (SMOG) System to Improve CBCT for IGRT and ART

All cancers but non-melanoma skin cancer

Tina Yuan

A systematic dissection of oncogenic KRAS signaling for target identification and therapeutic development

Melanoma of skin All cancers but non-melanoma skin cancer

Anne-Claude Gingras

A systems approach towards the therapeutic modulation of the acetylome

Melanoma of skin All cancers but non-melanoma skin cancer

Gerald R. Crabtree

ATP-Dependent Chromatin Remodeling in Human Malignancy

Melanoma of skin All cancers but non-melanoma skin cancer

James Kochenderfer

Autologous T cells Transduced with an Anti-CD19 Chimeric Antigen Receptor

Hematology and hematologic malignancies

Leslie M Shaw

Autophagy-independent function of Beclin 1 in Breast Cancer

Angela Parrish

Axin-induced Wnt signaling in mouse embryogenesis and Wnt-related cancers

Colorectum Breast

Keila Enitt Torres

Axl receptor signaling in MPNST; potential node for therapy

Joseph Culotti

Axon guidance and cell migration mechanisms in C. elegans

Melanoma of skin All cancers but non-melanoma skin cancer

Susan Gottesman

Bacterial Functions Involved in Cell Growth Control

All cancers but non-melanoma skin cancer

Kevin Michael Haigis

Basic and Translational studies of Ras-mutant colorectal cancer

Radoslav Goldman

Basic Cancer Research in Cancer Health Disparities

Aimin Jiang

b-catenin in vaccine-induced anti-tumor CD8 T cell immunity

Melanoma of skin All cancers but non-melanoma skin cancer

Clark W Distelhorst

Bcl-2 Function on the Endoplasmic Reticulum

Non-Hodgkin lymphoma Multiple myeloma and immunoproliferative diseases Leukaemia

Hematology and hematologic malignancies Pathology

Tomasz Skorski

BCR/ABL-PI-3k-ROS pathway induce genomic instability ....

Hematology and hematologic malignancies Pathology

Anthony E Oro

BEG4/MIM Function in Epithelial Neoplasia

Non-Melanoma skin cancer

Paul B. Jacobsen

Behavioral Oncology Education & Career Development

Melanoma of skin All cancers but non-melanoma skin cancer

Brian K. Kobilka

Beta2 Adrenoceptor Structure and Mechanism of Activation

Melanoma of skin All cancers but non-melanoma skin cancer

John Nicholas

BH3-only Protein Targeting by HHV-8

Non-Hodgkin lymphoma Kaposi sarcoma Hodgkin lymphoma

Suresh Ambudkar

Biochemical Analysis of Multidrug Resistance-linked Transport Proteins

Hematology and hematologic malignancies Pathology

Lawrence Samelson

Biochemical Basis of T Cell Activation

Hodgkin lymphoma

Hematology and hematologic malignancies Pathology

Michael Maurizi

Biochemistry of Energy-Dependent (Intracellular) Protein Degradation

All cancers but non-melanoma skin cancer

Arash Hatefi

Bioengineering a Safe and Efficient Vector Technology for Stem Cell Transfection

Melanoma of skin All cancers but non-melanoma skin cancer

Mikhail Shapiro

Biogenic Gas Nanostructures As Molecular Imaging Reporters For Ultrasound

Melanoma of skin All cancers but non-melanoma skin cancer

Giovanni Luigi Parmigiani

Bioinformatics Tools for Genomic Analysis of Tumor and Stromal Pathways in Cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Karl Munger

Biological Activity of HPV E7 in Human Epithelial Cells

Channing J Der

Biological Activity of Ras Oncogenes

Gordon B. Mills

Biological annotation of TCGA data

Melanoma of skin All cancers but non-melanoma skin cancer

Michael Bustin

Biological Functions of Chromosomal Proteins

Prostate Liver and intrahepatic bile ducts Leukaemia Breast

Radiation Oncology Pediatric oncology or childhood cancer

Federico Bernal

Biological Implications and Translational Applications of HDMX Inhibition

Non-Melanoma skin cancer

Soheil Meshinchi

Biology and Prognostic Implications of FLT3 Mutations in AML

Crystal Mackall

Biology and Therapy of Lymphopenia

All cancers but non-melanoma skin cancer

Gilbert Smith

Biology of Mammary Gland Development and Tumorigenesis

Joseph Steven Lipsick

Biology of the Myb-MuvB Oncoprotein Tumor Suppressor Protein Complex

Melanoma of skin All cancers but non-melanoma skin cancer

Joshua Labaer

Biomarker Detection Using NAPPA Tumor Antigen Arrays

Patrick Hwu

Biomarkers and Resistance Mechanisms in Melanoma T-cell Therapy

Melanoma of skin

Carlos O Esquivel

Biomarkers for Post-Transplant Lymphoproliferative Disorders in Children

Non-Hodgkin lymphoma Hodgkin lymphoma

Pediatric oncology or childhood cancer

Curtis Harris

Biomarkers in Cancer Diagnosis, Prognosis, and Therapeutic Outcome

Trachea, bronchus and lung

Pathology Pediatric oncology or childhood cancer

Ruth Nussinov

Biomolecular Recognition and Binding Mechanisms

All cancers but non-melanoma skin cancer

Xinhua Ji

Biomolecular Structure and Mechanism, Structure-Based Drug Design

All cancers but non-melanoma skin cancer

Dolph Hatfield

Biosynthesis of Selenocysteine and Its Incorporation into Protein

All cancers but non-melanoma skin cancer

John Beulter

Biotechnology Engagement Program (BTEP) Supporting Scientific Redirection Through the Engagement of CIS Former Biological Weapons Scientists in Public Health Related Research Working in Collaboration with U.S. Scientists

All cancers but non-melanoma skin cancer

David FitzGerald

Bio-Therapies for the Treatment of Cancer

Trachea, bronchus and lung Leukaemia Colorectum

Shrikant Anant

Bitter Melon Component and Colon Cancer Prevention

Timothy N Bullock

BLIMP-1 Mediated Regulation of CD8+ TIL

Melanoma of skin

Kevin Brulois

Blocking an Endogenous Inhibitor of Anti-tumor Leukocyte Recruitment

Melanoma of skin

Samuel Strober

Blood Stem Cell Transplantation as Immunotherapy

Non-Hodgkin lymphoma Leukaemia Hodgkin lymphoma

Sue-Hwa Lin

Bone Marrow-Derived Mesenchymal Stem Cells in Prostate Cancer-Induced Bone Remodeling

Sue-Hwa Lin

Bone Microenvironment on Dormancy of Metastatic Prostate Cancer Cells

Carmelo Nucera

BRAFV600E and VEGFR2 synergize to trigger papillary thyroid cancer progression

Candece L Gladson

Brain Endothelial TNF-R1 Can Function to Inhibit Angiogenesis

Brain, nervous system

Fergus J Couch

BRCA1 and BRCA2 Missense Mutations and Breast Cancer Risk

Mathieu Lupien

Breast and Prostate Cancer Risk SNPs Regulate FoxA1 and Nuclear Receptor Activity

Prostate Breast

Susan L Teitelbaum

Breast Cancer Genomics in Windows of Susceptibility to Endocrine Disruptors

Leo Masamba

Breast Cancer Receptor Study : Targeting HIV Associated Lymphoma in Malawi

Non-Hodgkin lymphoma Breast

Mara A Schonberg

Breast Cancer Risk Factors Among Women Aged 75 and Older

Claudia Fischbach

Breast Microcalcifications and their Role in Breast Cancer Bone Metastasis

Prashant Desai

Bridging KSHV Capsids to the Nuclear Egress Complex

Federico Bernal

Broadening the Utility of Stapled Peptides through Chemical Optimization

All cancers but non-melanoma skin cancer

Radiation Oncology

Nicholas Restifo

Building on the Success of the Adoptive Immunotherapy of Cancer

All cancers but non-melanoma skin cancer

Xuehong Zhang

Calcium Intake and Colorectal Cancer Incidence and Survival

Xiao-Tong Song

Cancer and Stroma-Targeted Immunotherapy with a Gentically Modified DC Vaccine

Melanoma of skin All cancers but non-melanoma skin cancer

Robert A Gatenby

Cancer as a Complex Adaptive System

Melanoma of skin All cancers but non-melanoma skin cancer

Keith Syson Chan

Cancer-associated fibroblast in the regulation of bladder cancer stem cells

Hisataka Kobayashi

Cancer-Cell Specific Therapy: Photo-Immunotherapy

All cancers but non-melanoma skin cancer

Ronald Anthony Depinho

Cancer Center Support (CORE) Grant

Melanoma of skin All cancers but non-melanoma skin cancer

Palliative Care

Stuart L Schreiber

Cancer dependencies associated with genomic alterations and targeted by small molecules

Melanoma of skin All cancers but non-melanoma skin cancer

Kim O'Neill

Cancer Immunology Research at Brigham Young University

Trachea, bronchus and lung Prostate Leukaemia Breast

Robert S. Dipaola

Cancer Institute of New Jersey - Cancer Center Support Grant

Melanoma of skin All cancers but non-melanoma skin cancer

Snorri Thorgeirsson

Cancer Stem Cells and Human Liver Cancer

Liver and intrahepatic bile ducts

Vicki Huff

Cancer Stem Cells in Mouse and Human Wilm's Tumor

All cancers but non-melanoma skin cancer

Pediatric oncology or childhood cancer

Marco A Marra

Cancer transcriptome characterization using massively parallel DNA sequencing

All cancers but non-melanoma skin cancer

Joel N Hirschhorn

CANDIDATE GENE STUDIES OF OBESITY GUIDED BY WHOLE GENOME ASSOCIATION DATA

Melanoma of skin All cancers but non-melanoma skin cancer

Joseph Barchi

Carbohydrate Antigen-bearing Nanoparticles for Anti-adhesives and Tumor Vaccines

Pancreas Breast All cancers but non-melanoma skin cancer

Mark I Greene

Carbohydrate Antigenic Biomarkers for Epithelial Cancers

Prostate Breast

Jeffrey Gildersleeve

Carbohydrate Microarray Profiling of Glycan-Binding Antibodies and Lectins

Robert J. Gillies

Causes & Consequences of Acid pH in Tumors

Melanoma of skin All cancers but non-melanoma skin cancer

Kelvin P. Lee

CD28-mediated Regulation of Multiple Myeloma Cell Proliferation and Survival

Multiple myeloma and immunoproliferative diseases

Kelvin P Lee

CD28-Mediated Regulation of Multiple Myeloma Cell Proliferation and Survival

Multiple myeloma and immunoproliferative diseases

Hematology and hematologic malignancies Pathology

Abigail Rachele Mateo

C. elegans p53 family transcription factor has roles in meiotic recombination and DNA interstrand crosslink repair

Melanoma of skin All cancers but non-melanoma skin cancer

Minna Roh

Cell Biological Mechanisms of Melanoma Cell Motility in vivo

Melanoma of skin

Melanie Hayden

Cell-free tumor DNA in cerebral spinal fluid decodes tumors of the central nervous system

Brain, nervous system

Robert J Wechsler-Reya

Cellular and Genetic Basis of Anaplastic Medulloblastoma

Brain, nervous system

Pediatric oncology or childhood cancer

Christopher Y Park

Cellular and molecular basis of microRNA-29a Induced Acute Myeloid Leukemia

Zijie Sun

Cellular and Molecular Properties Of PINs In Prostate Tumorigenesis

Katharina Schlacher

Cellular and Molecular Tumorsuppressor Processes Uncovered by DNA Fork Protection

Melanoma of skin All cancers but non-melanoma skin cancer

Parijat Bhatnagar

Cellular biofactories for therapeutic protein synthesis in tumor microenvironment

Rosalie C Sears

Cellular Mechanisms Controlling Myc Protein Stability

All cancers but non-melanoma skin cancer

Philip C Trackman

Cellular or Extracellular Targeting of Lysyl Oxidase Propeptide for Oral Cancer

Lip, oral cavity

James W Curran

Center for AIDS Research at Emory University

All cancers but non-melanoma skin cancer

David H Haussler

Center for Big Data in Translational Genomics

Leukaemia Breast

Walter J Atwood

Center for Cancer Signaling Networks

Melanoma of skin All cancers but non-melanoma skin cancer

Mary V. Relling

Center for Precision Medicine in Leukemia (CPML)

Hector Dantes

Center for Statistics and Quantitative Infectious Diseases

All cancers but non-melanoma skin cancer

Peter Kent Jackson

Centriolar-ciliary signaling mechanisms in tissue regeneration and differentiation

Melanoma of skin All cancers but non-melanoma skin cancer

Yi Tang

Characterization and Engineering of Fungal Megasynthases

Melanoma of skin All cancers but non-melanoma skin cancer

David C Lyden

Characterization and Functional Analysis of Breast Cancer Secreted Exosomes in Ma

M. James You

CHARACTERIZATION AND TARGETED THERAPY OF T-ALL DEFICIENT FOR PTEN AND INK4A/ARF

Kaiyi Li

Characterization and targeting BRIT1 deficiency in breast cancer

Quynh-Thu Xuan Le

Characterization and Targeting the GDNF and Other Pathways in Salivary Stem Cells

Other pharynx Oesophagus Nasopharynx Lip, oral cavity Larynx

Radiation Oncology

Joann B Sweasy

Characterization of a DNA Polymerase Beta Deficient Mouse

All cancers but non-melanoma skin cancer

Radiation Oncology

Rachelle W Johnson

Characterization of breast cancer dormancy in bone

Wei Zhang

Characterization of Colorectal Cancer Genome by Deep Sequencing and Functional Validation of Selected Candidates

Ada Leung

Characterization of Genes and Pathways Conferring Cytoprotective Responses and Validation of Potential Targets that will Enhance First-Line Platinum-Based Chemotherapy in Non-Small Cell Lung Cancer

Trachea, bronchus and lung

Carolyn S. Lee

Characterization of Homeostatic Regulators Disrupted in Epidermal Neoplasia

Melanoma of skin Non-Melanoma skin cancer

Mark R Philips

Characterization of lcmt in Animal Models of Cancer

Stomach Pancreas

David Kozono

Characterization of lung cancer radiosensitizers from genome-wide RNAi screens

Trachea, bronchus and lung

Jetze J Tepe

Characterization of Non-Competitive Proteasome Binding

Multiple myeloma and immunoproliferative diseases

Hematology and hematologic malignancies Pathology

Wei Zhang

Characterization of oncogenic FGFR3-TACC3 fusion gene in glioblastoma

Brain, nervous system

Matthew Robert Ramsey

Characterization of Oncogenic Transcription Factor-Associated Proteins in SCC

All cancers but non-melanoma skin cancer

Xiaosong Wang

CHARACTERIZATION OF RECURRENT ADJACENT GENE TRANSLOCATIONS IN BREAST CANCER

Jacqueline Barlow

Characterization of replication-mediated DNA damage in B lymphocytes

Non-Hodgkin lymphoma

Hematology and hematologic malignancies Pathology

David T Breault

Characterization of Telomerase Expressing Intestinal Stem Cells

Elisabeth D Martinez

Characterization of the biological activities of novel epigenetic modulators

Trachea, bronchus and lung

Characterization of the Biological Activities of Novel Epigenetic Modulators

Trachea, bronchus and lung

Daniel McVicar

Characterization of the Expression and Ligands of KIR3DS2

Hematology and hematologic malignancies Pathology

Alvaro Monteiro

Characterization of Variants of Uncertain Significance in BRCA1 and BRCA2

C Marcelo Aldaz

Characterization of WWOX, the Cancer Gene Spanning FRA16D

Shiaw-Yih Lin

Characterizing and Targeting CHD4 Deficiency in Endometrial Cancer

Michael Kharas

Characterizing MSI2 in leukemia

Alvaro Monteiro

Charting the BRCT Domain Network

Anne Goldfeld

Checkpoints of TNF Gene Regulation

Melanoma of skin All cancers but non-melanoma skin cancer

James K Chen

Chemical genetic dissection of Hipk4-dependent Hedgehog pathway activation

Trachea, bronchus and lung Non-Melanoma skin cancer Leukaemia Brain, nervous system

Christopher J Ott

Chemical Modulation of Chromatin Signaling in Lymphoid Malignancies

Non-Hodgkin lymphoma Leukaemia Hodgkin lymphoma

Matthew Bogyo

Chemical Probes for Specific Targeting of Matrix Metallo Proteases

Yongcheng Song

Chemical Probes Targeting Gliomas with IDH Mutation

Brain, nervous system

Augustin Luna

Chemogenomic Analysis of the NCI Therapeutic Compound Database

Melanoma of skin All cancers but non-melanoma skin cancer

Ann Richmond

Chemokine Signals in the Premetastatic Niche Inhibit Metastasis

Seema Singh

Chemoprotective Role of Silver Nanoparticles in UV Radiation-Induced Skin Carcino

Non-Melanoma skin cancer

Pathology Radiation Oncology

Mariano Sebastian Viapiano

Chimeric Anti-Fibulin-3 Reagents For Targeted Therapy Of Glioblastoma

Brain, nervous system

Ramesh A Shivdasani

Chromatin and transcriptional control of LGR5+ crypt base stem cells

Gordon Hager

Chromatin Remodeling Proteins

Gordon Hager

Chromatin Structure and Gene Expression

All cancers but non-melanoma skin cancer

Michael Bustin

Chromosomal Proteins and Chromosomal Functions

All cancers but non-melanoma skin cancer

Jonathan A. Cooper

Chromosome Metabolism and Cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Edward Cowen

Chronic Graft-Versus-Host Disease

All cancers but non-melanoma skin cancer

Radiation Oncology

Scott Durum

Chronic Inflammation and Carcinogenesis

Matthew Davis

Classification and functional annotation of endogenous siRNAs and other small RNAs

Sean V Tavtigian

Classifying DNA Mismatch Repair Gene Variants of Unknown Significance

Frank Maldarelli

Clinical Interventional Studies of HIV Reservoirs

All cancers but non-melanoma skin cancer

Radiation Oncology

Frank Maldarelli

Clinical Interventional Studies of HIV Reservoirs – Rockville

Radiation Oncology

William Figg

Clinical Pharmacogenetics

Effie W Petersdorf

Clinical Significance of MHC Haplotypes in HCT

Keping Xie

Clinical Significance of Pancreatic Cancer Differentiation and Dedifferentiation

Susan Bates

Clinical Studies to Circumvent Drug Resistance

Trachea, bronchus and lung Kidney, renal pelvis and ureter Breast Brain, nervous system

Isaac Brownell

Clinical Treatment of Advanced Merkel Cell Carcinoma

Melanoma of skin

James Y. Chen

Clonal Evolution and Prospective Isolation of Myelodysplastic Syndrome Initiating

Kristen Elizabeth Norman Scott

c-MYC dependent regulation of de novo lipogenesis in B-cell lymphomagenesis

Non-Hodgkin lymphoma Hodgkin lymphoma

Tim Alan Ahles

Cognition In Older Breast Cancer Survivors: Treatment Exposure, APOE, & Smoking

Gregory J Hannon

Cold Spring Harbor Laboratory Cancer Research Center

Trachea, bronchus and lung Pancreas Non-Hodgkin lymphoma Liver and intrahepatic bile ducts Breast

Peter Aplan

Collaborative Pathways that Lead to Leukemia

Hematology and hematologic malignancies Pathology

Peter Aplan

Collaborative Pathways that Lead to Leukemia – Rockville

Hematology and hematologic malignancies Pathology

Valerie M Weaver

Collagen Remodeling and Tumor Progression

Nathalie Rivard

Colorectal Cancer Research (CANADA RESEARCH CHAIRHOLDER)

Thomas Ried

Colorectal Cancer Transcriptome: Effects of Genomic Instability and Aneuploidy

Radiation Oncology

Thomas Ried

Colorectal Cancer Transcriptome: Effects Of Genomic Instability And Aneuploidy

Radiation Oncology

Thomas Ried

Colorectal Cancer Transcriptome: Effects of Genomic Instability and Aneuploidy – Rockville

Radiation Oncology

Alfred Neugut

Columbia-South Africa Training Program for Research on Hiv-Associated Malignanci

Non-Hodgkin lymphoma Kaposi sarcoma

Rupal S Bhatt

Combating Resistance to Antiangiogenic Therapy in Renal Cell Carcinoma

Kidney, renal pelvis and ureter

Daniel Fowler

Combination Gene Therapy and Th1/Th2 Therapy

Non-Hodgkin lymphoma Leukaemia

Hematology and hematologic malignancies

Frank Jirik

Combining development of transgenic animals with the application of advanced phenotyping technologies (CANADA RESEARCH CHAIRHOLDER)

Investigator from Ludwig Boltzmann Gesellschaft (LBG)

Common Oncogenic Mechanisms in Multi-Partner Translocation Families in Acute Myeloid Leukemia

Lorenzo Cohen

Community-Based, Phase III Trial of acupuncture to treat chronic Xerostomia

Melanoma of skin All cancers but non-melanoma skin cancer

Radiation Oncology

Ashish Lal

Comparative Oncology program

All cancers but non-melanoma skin cancer

Chand Khanna

Comparative Oncology Program

Margaret A Shipp

Complementary Signaling Pathways In Hodgkin Lymphoma and Related Malignancies

Hodgkin lymphoma

Stuart Keith Calderwood

Complex Role of HSF1 in Breast Cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Edward E. Partridge

Comprehensive Cancer Center Core Support Grant

Melanoma of skin All cancers but non-melanoma skin cancer

Bruce Shapiro

Computational and Experimental RNA Nanobiology

All cancers but non-melanoma skin cancer

Benjamin Raphael

Computational Approaches for Structural Variation Studies in Genomes

Melanoma of skin All cancers but non-melanoma skin cancer

Byungkook Lee

Computational Biology

All cancers but non-melanoma skin cancer

Benjamin Raphael

Computational Characterization of Genetic Heterogeneity

Melanoma of skin All cancers but non-melanoma skin cancer

Jeffrey Mackeigan

Computational Model of Autophagy-Mediated Survival in Chemoresistant Lung Cancer

Trachea, bronchus and lung

Ekaterina Pletneva

Conformational Properties of Cytochrome c in Apoptosis

Melanoma of skin All cancers but non-melanoma skin cancer

Amy Paguirigan

Connecting Single Cell Heterogeneity to Clinical Descriptors of Clonal Evolution in Acute Myeloid Leukemia

Howard Young

Consequences of chronic Interferon-gamma expression on the host

Kidney, renal pelvis and ureter

Howard Young

Consequences of Chronic Interferon-Gamma Expression on the Host

All cancers but non-melanoma skin cancer

Valen Earl Johnson

Consistent Model Selection in the p>>n Setting

Colorectum Breast

Dipak Panigrahy

Controlling cancer with aspirin-triggered stimulation of resolution

Melanoma of skin All cancers but non-melanoma skin cancer

Dipak Panigrahy

Controlling Cancer with Aspirin-Triggered Stimulation of Resolution

Prostate Colorectum Breast

Dario C Altieri

Control of Apoptosis in Cancer by Survivin

Dipak Panigrahy

Control of Cancer and Metastasis by Endothelial-Derived Epoxyeicosatrienoic Acids

Breast Brain, nervous system

William G. Dunphy

Control of Cell Cycle Transitions

Melanoma of skin All cancers but non-melanoma skin cancer

Derek B. Sant'Angelo

Control of cytokine production by human NK cells

Dominique C Bergmann

Control of epidermal self-renewing populations by bHLH and MAPK regulatory system

Melanoma of skin All cancers but non-melanoma skin cancer

Investigator from French National Centre for Scientific Research (CNRS)

Control of the Homeostasis of Actin through Time: actin homeostasis during embryonic development by means of single-molecule imaging and simulation in C. elegans

Melanoma of skin All cancers but non-melanoma skin cancer

Ryan Alexander Flynn

CONTROL OF TRANSCRIPTION BY THE 7SK RNA IN BREAST CANCER

Suzanne J Baker

Cooperating Pathways in Gliomagenesis

Brain, nervous system

Zhimin Lu

Coordinated Regulation of Glycolysis and Mitochondrial Metabolism in Tumorigenesis

All cancers but non-melanoma skin cancer

Israel David Goldman

Core Support for Cancer Center

Melanoma of skin All cancers but non-melanoma skin cancer

Amod Sarnaik

Co-Stimulation to Enhance Adoptive Cell Therapy for Metastatic Melanoma

Melanoma of skin

Estela Jacinto

Cotranslational Functions of MTOR

Melanoma of skin All cancers but non-melanoma skin cancer

Julie Lessard

CRC Tier 1 - BAF subunits assembled into functionally specialized complexes in the developing hemopoietic system and in leukemia

Michael Tyers

CRC Tier 1 - Biological networks in human health and disease

Melanoma of skin All cancers but non-melanoma skin cancer

Tak Mak

CRC Tier 1 - Determining why mutations of the metabolic enzyme isocitrate dehydrogenase cause leukemias and brain cancers

Leukaemia Brain, nervous system

Lewis Kay

CRC Tier 1 - Develop new Nuclear Magnetic Resonance Spectroscopy based techniques for relating molecular motions to function

Melanoma of skin All cancers but non-melanoma skin cancer

Daniel Durocher

CRC Tier 1 - DNA damage

Melanoma of skin All cancers but non-melanoma skin cancer

Aaron Goodarzi

CRC Tier 1 - Molecular pathways underlying DSB repair

Melanoma of skin All cancers but non-melanoma skin cancer

Radiation Oncology

Mark Lathrop

CRC Tier 1 - New research programme to understand the genetic causes of human diseases such as cancer, asthma and heart disease

Melanoma of skin All cancers but non-melanoma skin cancer

Benjamin Neel

CRC Tier 1 - Treatments for RASopathies and cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Laurence Pelletier

CRC Tier 1 - Understand how centrosome duplicate, grow and participate in the formation of mitotic spindles and cilia

Melanoma of skin All cancers but non-melanoma skin cancer

Sherif Abou Elela

CRC Tier 1 - Use yeast as a model system to understand how changes in RNA processing and stability influences cell growth

Melanoma of skin All cancers but non-melanoma skin cancer

Steve Bilodeau

CRC Tier 2 - Defining how the cellular operating system is regulated

Melanoma of skin All cancers but non-melanoma skin cancer

Maya Shmulevitz

CRC Tier 2 - Human Reovirus

Melanoma of skin All cancers but non-melanoma skin cancer

Jason Moffat

CRC Tier 2 - Identify novel cancer cell vulnerabilities

Melanoma of skin All cancers but non-melanoma skin cancer

Patrick O'Donoghue

CRC Tier 2 - Protein modifications Signalling

Melanoma of skin All cancers but non-melanoma skin cancer

Francois Bachand

CRC Tier 2 - RNA synthesis

Melanoma of skin All cancers but non-melanoma skin cancer

Stefan Taubert

CRC Tier 2 - Studying Mediator Components

Melanoma of skin All cancers but non-melanoma skin cancer

Sarah Hughes

CRC Tier 2 - Understanding how Merlin acts as a tumour suppressor

Melanoma of skin All cancers but non-melanoma skin cancer

Tamra Werbowetski-Ogilvie

CRC Tier 2 - Using human stem cells to study glioblastoma multiforme (GBM) and medulloblastoma

Brain, nervous system

Daniel M Sullivan

CRM1 INHIBITORS SENSITIZE MULTIPLE MYELOMA CELLS TO TOPOISOMERASE II AND PROTEASOME INHIBITORS

Multiple myeloma and immunoproliferative diseases

Vania Braga

Cross-talk between Ajuba and Rac signalling in the stabilization of cadherin adhesion

Melanoma of skin All cancers but non-melanoma skin cancer

Eric Collisson

Crucial Microenvironmental Cofactors for Pancreatic Cancer Pathogenesis

Rachael Ann Clark

CTCL immunobiology: lessons from alemtuzumab

Non-Hodgkin lymphoma

Mizuki Nishino

CT Volume Measurement of Lung Cancer treated with Erlotinib: Genomic Correlation

Trachea, bronchus and lung

Katy Rezvani

Curative Cell-based Therapies for Chronic Lymphocytic Leukemia

Hematology and hematologic malignancies

Peter Sicinski

Cyclin-Dependent Kinases in Oncogenesis

Scott Durum

Cytokines and T Cell Development

Non-Hodgkin lymphoma Leukaemia

Hematology and hematologic malignancies Pediatric oncology or childhood cancer

George Pavlakis

Cytokines in AIDS and Cancer

All cancers but non-melanoma skin cancer

Vineet KewalRamani

Cytoplasmic-Nuclear Trafficking of HIV-1

All cancers but non-melanoma skin cancer

Bruce R Blazar

Cytotoxic-T-Lymphocyte (CTL) Therapy of Acute Myeloid Leukemia (AML)

Hematology and hematologic malignancies Pathology

Joseph H Mccarty

Deciphering mechanisms of perivascular tumor cell invasion in glioblastoma

Brain, nervous system

Investigator from Institut d'Investigació Biomédica de Bellvitge

Deciphering PI3K biology in health and disease

Rohit Prakash

Deciphering the epistatic relationships of RAD51 Paralogs in mammary epithelium

Zhimin Lu

Deciphering the role of Cdc25A in cancer metabolism.

Melanoma of skin All cancers but non-melanoma skin cancer

George Calin

Deciphering the Role of Non-coding RNA in Chronic Lymphocytic Leukemia

Hematology and hematologic malignancies Pathology

Pascale Willem

Deciphering the roles of chromatin modifiers in germline aging

Melanoma of skin All cancers but non-melanoma skin cancer

Brendan D. Manning

Decoding and targeting the PI3K-mTOR signaling network in cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Joseph Avruch

Decoding the MST1 and MST2 Kinases in Cellular Physiology and Tumor Suppression

Liver and intrahepatic bile ducts

Pier Paolo Pandolfi

Deconstruction and in vivo functionalization of the ceRNA cancer network (PQ-11)

Melanoma of skin All cancers but non-melanoma skin cancer

Harlan S. Robins

Deep sequencing for minimal residual disease detection in Acute Lymphoblastic Leukemia

Jordan Meier

Defining and Manipulating Epigenomic Regulators in Endogenous Systems

All cancers but non-melanoma skin cancer

Ronglai Shen

Defining a novel subtype of luminal-TP53 mutant breast cancer with poor prognosis

Melanoma of skin All cancers but non-melanoma skin cancer

Kj Patel

Defining defective DNA repair in Fanconi Anaemia

Melanoma of skin All cancers but non-melanoma skin cancer

Hematology and hematologic malignancies

Daniela M Dinulescu

Defining microRNA Signatures for Early Detection in BRCA-Mutated Ovarian Cancer

Neil J. Ganem

Defining novel pathways that arrest genetically unstable tetraploid cells

Melanoma of skin All cancers but non-melanoma skin cancer

Steen Henning Hansen

Defining oncogenic capacities of PAK7 mutations in human cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Brett Stewart Carver

Defining Response and Resistance to PI3K and AR inhibition in Prostate Cancer

Matthew L Freedman

Defining the epigenetic landscape in human prostate cancer

Catherine Ju-Ying Wu

Defining the impact of clonal evolution on chronic lymphocytic leukemia

Catherine Ju-Ying Wu

Defining the Impact of Clonal Evolution on Chronic Lymphocytic Leukemia

Hematology and hematologic malignancies Pathology

Andrew Caleb Hsieh

Defining the role of eIF4F in metastatic castration resistant prostate cancer

Charles L. Sawyers

Defining the Role of ERG in Modulating the AR Cistrome and Antiandrogen Sensitivity

Fang Wang

Defining the role of human isomiR-181a in myelodysplastic syndromes

Melanoma of skin All cancers but non-melanoma skin cancer

Peter S. Choi

Defining the role of RBM10 in RNA processing and tumor suppression

Melanoma of skin All cancers but non-melanoma skin cancer

A. K. M. Nur-Ur Rahman

Defining the role of T cell metabolism in HIV-induced chronic immune activation and immune dysfunction.

Melanoma of skin All cancers but non-melanoma skin cancer

David B. Solit

Defining the temporal sequence of PI3K pathway mutations in bladder cancer

Sharon Y. R. Dent

Defining USP22 Functions During Mammalian Development

Melanoma of skin All cancers but non-melanoma skin cancer

Shawn B Bratton

Degradation mechanisms for inhibitor of apoptosis proteins and their antagonists

Melanoma of skin All cancers but non-melanoma skin cancer

Ken Chen

Delineating Heterogeneous Structural Complexity in Cancer Genomes

Melanoma of skin All cancers but non-melanoma skin cancer

Inanc Birol

De Novo Assembly Tools: Research with Unbiased Engines (DNA-TRUE)

Melanoma of skin All cancers but non-melanoma skin cancer

Investigator from University of Padua

DE NOVO GENERATION OF SOMATIC STEM CELLS: REGULATION AND MECHANISMS OF CELL PLASTICITY

Melanoma of skin All cancers but non-melanoma skin cancer

Gregory F Oxenkrug

Depression, insulin resistance and xanthurenic acid in hepatitis C virus patients

Liver and intrahepatic bile ducts

Liam Hudson

Design and synthesis of Histone Lysine Methyltransferases inhibitors as epigenetic modulators

Melanoma of skin All cancers but non-melanoma skin cancer

Terrence Burke

Design and Synthesis of HIV Integrase as Potential Anti-AIDS Drugs

All cancers but non-melanoma skin cancer

Stuart Rankin

Design and synthesis of medium-ring compounds to target nucleotide binding sites

Melanoma of skin All cancers but non-melanoma skin cancer

James Mui

Design and synthesis of small molecule inhibitors of NEK family Ser/Thr protein kinases

Melanoma of skin All cancers but non-melanoma skin cancer

Joel Schneider

Design and Utility of Novel Proteinaceous Biomaterials

All cancers but non-melanoma skin cancer

Ray-Bing Chen

Designing Efficient Designs under Model Uncertainty for Biological Studies

Melanoma of skin All cancers but non-melanoma skin cancer

Sung Wan Kim

Design of Oncolytic Adenovirus Conjugated with Novel Polymer for Cancer Treatment

Prostate Colorectum

Marco Mangone

Detection and validation of miRNA targets in breast cancer

Mona Batish

Detection of Chromosomal Translocations by Single Molecule RNA Imaging

Bakhos A Tannous

Detection of NSCLC-derived Mutant RNA in Platelets

Trachea, bronchus and lung

Allan Weissman

Determining the Fate of Transmembrane Proteins

Sarcoma Trachea, bronchus and lung Melanoma of skin Breast All cancers but non-melanoma skin cancer

Joel Pearson

Determining the molecular pathways that regulate mammalian cell competition

Melanoma of skin All cancers but non-melanoma skin cancer

Jens G Lohr

Determining the mutational landscape of circulating multiple myeloma cells

Multiple myeloma and immunoproliferative diseases

Jacob Houghton

Developing an Anti-sialyl-Lewisa Diabody for ImmunoPET Imaging of Pancreas Cancer

Xiaole Shirley Liu

Developing Informatics Technologies to Model Cancer Gene Regulation

Melanoma of skin All cancers but non-melanoma skin cancer

Nicholas Restifo

Developing New Immunotherapies Based of CD4+ T Cells

All cancers but non-melanoma skin cancer

H Leighton Grimes

Developing Novel STAT5 Protein Inhibitors for Treatment of Leukemias

Hematology and hematologic malignancies Pathology

John A Bartlett

Developing Research Capacity in Africa for Studies on HIV-Associated Malignancies

Non-Hodgkin lymphoma Kaposi sarcoma Hodgkin lymphoma Cervix uteri All cancers but non-melanoma skin cancer

Nathanael S Gray

Developing Selective EphA2 Inhibitors for the Treatment of Cancer

Trachea, bronchus and lung Melanoma of skin Breast

Nathanael Schiander Gray

Development and Application of Selective Covalent Cdk7 Inhibitors

Melanoma of skin All cancers but non-melanoma skin cancer

Investigator from Humanitas Research Hospital

Development and Evaluation of Nanomedicines for Cancer Treatment through Immunomodulation: Targeting Tumor-Associated Macrophages

Melanoma of skin All cancers but non-melanoma skin cancer

Alfred Singer

Development and Function of Regulatory T Cells

All cancers but non-melanoma skin cancer

Beatriz Sosa-Pineda

Development, cellular plasticity and homeostasis of the exocrine pancreas

Douglas C Marchion

Development of a Genomic Expression Signature Associated with Chemoresistance

Paul Krzyzanowski

Development of a genomic signature to identify progression of Barrett's Esophagus to Esophageal Adenocarcinoma

Michael J Galko

Development of a mechanical nociceptive sensitization model in Drosophila

Melanoma of skin All cancers but non-melanoma skin cancer

William Figg

Development of Angiogenesis Inhibitors

Prostate All cancers but non-melanoma skin cancer

Mitchell Ho

Development of antibody-based cancer therapies

Liver and intrahepatic bile ducts

Hiroaki Mitsuya

Development of Antiviral Therapy of HIV-1 Infection

All cancers but non-melanoma skin cancer

Hiroaki Mitsuya

Development of Antiviral Therapy of HIV-1 Infection – Rockville

All cancers but non-melanoma skin cancer

Fraser Symmans

Development of A Predictive Genomic Diagnostic Test for Survival Benefit from Everolimus (mTOR Inhibitor) Combined with Endocrine Therapy for Metastatic HR+/HER- Breast Cancer

John Martin Brown

Development of Clinical Strategies to Prevent GBM Recurrences After Radiotherapy

Melanoma of skin All cancers but non-melanoma skin cancer

Radiation Oncology

Nathanael Schiander Gray

Development of covalent PIP4K2 inhibitors for the treatment of p53 deficient lung tumors

Trachea, bronchus and lung

William Figg

Development of Drugs that Target Prostate Cancer

Robert D Schreiber

Development Of Genomics Based Personalized Cancer Immunotherapy

All cancers but non-melanoma skin cancer

Ira Pastan

Development of Improved Mesothelin Targeted Immunotoxins and other Tumor Specific Targeted Immunotoxins Using Proprietary Targeting Moieties

All cancers but non-melanoma skin cancer

Kyung Lee

Development of Inhibitors Targeting Plk1 Polo-Box Domain

All cancers but non-melanoma skin cancer

Rasha Guneidy

Development of multidrug resistance to beta-lactam antibiotics

All cancers but non-melanoma skin cancer

Hiroaki Mitsuya

Development of Novel Agents Active against Hepatitis B Virus

Liver and intrahepatic bile ducts Leukaemia

Vinay Pathak

Development of Novel Therapeutics by Targeting Vif-APOBEC3 Interactions

All cancers but non-melanoma skin cancer

Benjamin Levine Ebert

Development of Novel Therapeutic Strategies in Human Leukemias

Spencer Martin

Development of personalized vaccines targeting tumour-specific mutations

Melanoma of skin All cancers but non-melanoma skin cancer

Robert Kreitman

Development of Recombinant Toxins to Treat Hematologic Malignancies

Hematology and hematologic malignancies Pediatric oncology or childhood cancer

Chandra Bartholomeusz

Development of Targeted Therapy for ERK Pathway in Breast Cancer

Lalage Wakefield

Development of TGF-beta antagonists for cancer therapy

Marie C. Lee

Development of the Malignancy-Risk Gene Signature Assay for Predicting Breast Cancer Risk

Gregory Chen

Development of the MetaGx computational platform for meta-analysis of cancer molecular subtypes

Melanoma of skin All cancers but non-melanoma skin cancer

Shoukat Dedhar

Development of therapeutic antibodies targeting carbonic anhydrase IX (CAIX)

Philip W Kantoff

DF/HCC SPORE in Prostate Cancer

Larry Keefer

Diazeniumdiolates as Broad-Spectrum Anticancer Agents

Brain, nervous system

Vinata B Lokeshwar

Dietary Combination For Prevention of Metastatic Renal Cell Carcinoma

Kidney, renal pelvis and ureter

Stacey Ann Missmer

Dietary factors and risk of uterine fibroids

Philip N. Tsichlis

Differential regulation of RNA processing by Akt isoforms

Trachea, bronchus and lung

Theresa A Guise

Differential TGF-Beta Signaling in Bone Microenviroment: Impact on Tumor Growth

Prostate Melanoma of skin Breast

Differentiation of Granulocytes and Macrophages

Non-Hodgkin lymphoma Multiple myeloma and immunoproliferative diseases Hodgkin lymphoma

Hematology and hematologic malignancies Pathology

Mickie Bhatia

Differentiation of human stem cells to endpoint cell types (CANADA RESEARCH CHAIRHOLDER)

Melanoma of skin All cancers but non-melanoma skin cancer

Harold M Swartz

Direct and Repeated Clinical Measurement of pO2 for Enhancing Cancer Therapy

Other pharynx Non-Hodgkin lymphoma Cervix uteri Breast Brain, nervous system

Radiation Oncology

Mark Y Chiang

Direct coregulation of Notch1 by Zmiz1 in T-cell leukemia

Hematology and hematologic malignancies

Jordan Scott Orange

Directing Function at the Natural Killer Cell Secretory Immunological Synapse

Melanoma of skin All cancers but non-melanoma skin cancer

Kathleen M Mulder

Directional Motility and ERM Scaffolding in Pathfinder Pancreatic Carcinoma Cells

Thomas Westbrook

Discovering Genetic Networks of Triple-Negative Breast Cancer

Eduardo Vilar-Sanchez

Discovering New Targets for Chemoprevention in Familial Adenomatous Polyposis

Christopher I Li

Discovery and verification of novel biomarkers of colorectal cancer recurrence

David J Hunter

Discovery, Biology and Risk of Inherited Variants in Breast Cancer

Madonna Peter

Discovery of novel methylation biomarkers in circulating DNA of metastatic castration resistant prostate cancer patients to improve treatment decisions

Paul A Scheet

Discovery of Risk Loci and Genomics of Pancreatic Cancer through Exome Sequencing

Loren David Walensky

Dissecting and Targeting Deregulated Mitochondrial Apoptosis in Human Cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Katherine L B Borden

Dissecting eIF4E Dependent mRNA export

Hematology and hematologic malignancies Pathology

Jae-Il Park

Dissecting PAF, an Accelerator of Colorectal Cancer

Rakesh K Jain

Dissecting Pediatric Brain Tumor Microenvironment to Improve Treatment

Brain, nervous system

Radiation Oncology Pediatric oncology or childhood cancer

Alexander Palazzo

Dissecting the Molecular Mechanisms of the Alternative Nuclear Export and Endoplasmic Reticulum Targeting of Secretory mRNAs.

Melanoma of skin All cancers but non-melanoma skin cancer

Christine Mayr

Dissecting the role of alternative 3UTRs in cancer with 3-seq

Melanoma of skin All cancers but non-melanoma skin cancer

Selvendiran Karuppaiyah

Dissecting the Role of STAT3 and Targeting Ovarian Cancer

Hematology and hematologic malignancies Pathology

Tim Stearns

Dissecting the roles of TSC1 and TSC2 at the centrosome

Brain, nervous system

Mark Edward Hatley

Dissection of microRNA-21s role in non-small cell lung cancer

Trachea, bronchus and lung

Pediatric oncology or childhood cancer

Julie Secombe

Distinct Modes of Gene Regulation by KDM5

Melanoma of skin Colorectum Breast

Jonathan Strecker

Distinguishing double-strand DNA breaks from telomeres

Melanoma of skin All cancers but non-melanoma skin cancer

Margo G Haygood

Diverse Drug Lead Compounds from Bacterial Symbionts in Philippine Mollusks

Leukaemia All cancers but non-melanoma skin cancer

Juan Luis Mendoza

Diversifying interferon functions through combinatorial and structural biology

Melanoma of skin All cancers but non-melanoma skin cancer

Eric T. Kool

DNA-carbon Assemblies for Multispectral Imaging

Non-Hodgkin lymphoma Hodgkin lymphoma

Gabriel Sawakuchi

DNA Damage Response Induced by Therapeutic Proton and Carbon Ion Beams

All cancers but non-melanoma skin cancer

Radiation Oncology

Yves Pommier

DNA Repair, Cell Cycle Checkpoints and Apoptosis as Targets for Anticancer Drugs

Trachea, bronchus and lung Leukaemia Colorectum All cancers but non-melanoma skin cancer

Kenneth Kraemer

DNA Repair in Human Cancer-Prone Genetic Diseases

Non-Melanoma skin cancer

Jan Vijg

DNA Repair, Mutations and Cellular Aging

Melanoma of skin All cancers but non-melanoma skin cancer

Virginia A. Zakian

DNA Replication and Chromosome Structure in Yeast

Yves Pommier

DNA Topoisomerases as Nuclear and Mitochondrial Targets of Anticancer Drugs

Trachea, bronchus and lung Ovary Colorectum All cancers but non-melanoma skin cancer

Hematology and hematologic malignancies Pediatric oncology or childhood cancer

George Pavlakis

DNA Vaccines

All cancers but non-melanoma skin cancer

Tamara Dubowitz

Does a New Supermarket Improve Dietary Behaviors of Low-income African Americans?

All cancers but non-melanoma skin cancer

Dewi Harjanto

Does the RNA editor Apobec-1 shift microRNA targeting to a tumorigenic effect?

Melanoma of skin All cancers but non-melanoma skin cancer

Maria Jasin

Double-strand break repair and Translocations in mammalian cells

Melanoma of skin All cancers but non-melanoma skin cancer

Huiyan Zeng

Down Syndrome Candidate Region 1 isoform 1L in tumor growth and metastasis

Melanoma of skin All cancers but non-melanoma skin cancer

Eusebio Manchado-Robles

Drivers and dependencies as therapeutic targets in KRAS-mutant lung cancers

Trachea, bronchus and lung

Keiran Smalley

Drug Discovery Center

All cancers but non-melanoma skin cancer

Tarik F Massoud

Druggable p53 misfolding in cancer: A novel in vivo molecular imaging biosensor

Melanoma of skin All cancers but non-melanoma skin cancer

Elsa Flores

Drug Repositioning for Pharmacological Manipulation of p53 Family Members in p53 Mutant and Deficient Lung Tumors

Trachea, bronchus and lung

Pasi A Janne

Drug Resistance in Lung Cancer

Trachea, bronchus and lung

David A. Frank

Dual STAT3/NF-kB Inhibitors for Targeted Cancer Therapy

Melanoma of skin All cancers but non-melanoma skin cancer

Hamilton Courtney Hodges

Dynamic effects of cancer mutations on the mammalian SWI/SNF ATPase Brg

Melanoma of skin All cancers but non-melanoma skin cancer

Binghui Shen

Dynamic Functions of DNA2 Counteract DNA Replication Stresses and Tumorigenesis

All cancers but non-melanoma skin cancer

Radiation Oncology

Christopher H Contag

Dynamic Imaging of EMT in the Breast Cancer Microenvironment

David Bates

Dynamics and regulation of sister chromosome cohesion in E. coli.

Melanoma of skin All cancers but non-melanoma skin cancer

Joseph F Gera

Dysregulation of mTORC2 in gliomas

Brain, nervous system

Stefan Posse

Early Detection of Response to Treatment in Cancer by Hyperpolarized Metabolic MR

Trachea, bronchus and lung

Mara Tellez Rojo

Early Life Environmental Toxicant Exposure and Oral Health

Lip, oral cavity

Pediatric oncology or childhood cancer

Julia Kubanek

Ecological Leads for Drug Discovery from Marine Organisms

Leukaemia All cancers but non-melanoma skin cancer

Roy A Jensen

e-Decidete: Mobile Cessation Support for Latino Smokers in Mexico

Trachea, bronchus and lung

Rosemary Rochford

Effects of Malaria on EBV Persistence in Children

Non-Hodgkin lymphoma

Hematology and hematologic malignancies Pathology Pediatric oncology or childhood cancer

Boussiotis Vassiliki A

Effects of PGE2 on Reconstitution of Hematopoiesis and Immunity after UCBT

Melanoma of skin All cancers but non-melanoma skin cancer

Joyce M Slingerland

Effects of the PI3K Pathway on p27 Function and Cancer Progression

Bruce E. Johnson

EGFR Mutations in Non-Small Cell Lung Cancer

Trachea, bronchus and lung

Pinar Ozden Eser

EGFR T790M-mediated drug resistance in non-small cell lung cancer

Trachea, bronchus and lung

Bisrat G Debeb

Elucidate the role of miR-141 in brain metastasis from breast cancer

Timothy An-Thy Chan

Elucidating and targeting the molecular foundations of IDH mutant glioma

Brain, nervous system

Pengda Liu

Elucidating a Novel Akt Activation Mechanism for Targeted Prostate Cancer Therapy

Fariba Behbod

Elucidating Cellular Heterogeneity Among Cancer Stem Cells by Raman Spectroscopy

Radiation Oncology

Soma Sengupta

Elucidating Signaling Pathways for GABA-A Receptor Alpha5 in an Aggressive Subtype of Medulloblastomas

Brain, nervous system

Timothy An-Thy Chan

Elucidating the function of the widely inactivated phosphatase PTPRD in the molec

Brain, nervous system

Tiffany Y Hsu

Elucidating the functions of Bud31, an essential gene in Myc-driven breast cancer

Joel Alter

Elucidating the in vivo Role of Pyk2 in Cancer Metastasis

Cecilia M Williams

Elucidating the mechanism of ERbeta in colon carcinogenesis

Laura Alice Stransky

Elucidating the mechanism of mTORC1 activation by amino acids

Emilia Lim

Elucidating the Mechanisms by which Mutations in Histone Modifying Genes Contribute to Lymphomagenesis

Non-Hodgkin lymphoma Hodgkin lymphoma

Wei-Shau Hu

Elucidating the Mechanisms of Reverse Transcription and Recombination

All cancers but non-melanoma skin cancer

André Veillette

Elucidating the molecular mechanisms that control the functions of immune cells (CANADA RESEARCH CHAIRHOLDER )

Melanoma of skin All cancers but non-melanoma skin cancer

Piro Lito

Elucidating the regulation of mitosis by BRAF V600E in lung cancer

Trachea, bronchus and lung

Kristina Cotter

Elucidating the Role of Plasma Membrane V-ATPases in Breast Cancer Metastasis

Nya D Nelson

Elucidating the role of TIN2L at the telomere and in dyskeratosis congenita

Lip, oral cavity Leukaemia

Ping Chi

Elucidating the roles of ETV1 in the pathogenesis of GIST

Robert Rottapel

Elucidation of the role of the RhoGEF Lfc in human epithelial tumors

John Jessup

Embryonic Transcription Factor Function in Human Colorectal Cancer Stem Cells

Clare M Tempany

Enabling Technologies For MRI-Guided Prostate Interventions

Barth Demian Grant

Endocytosis and Recycling in C. elegans and Mammals

Melanoma of skin All cancers but non-melanoma skin cancer

Shiladitya Sengupta

Engineering a supramolecular platinum nanoparticle for pediatric cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Pediatric oncology or childhood cancer

Prashant Desai

Engineering Herpesviruses using Synthetic Genomics

Nasopharynx Hodgkin lymphoma

John B Sunwoo

Enhancement of Natural Killer Cell Effector Functions

Non-Hodgkin lymphoma Hodgkin lymphoma

Dihua Yu

Enhancing Chemo-Response in Triple-Negative Breast Cancer by Activiating T-Cell Response

Helen E. Heslop

Enhancing T Cell Therapy of Cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Paul M Thompson

ENIGMA Center for Worldwide Medicine, Imaging & Genomics

Leukaemia All cancers but non-melanoma skin cancer

Karin B Michels

Environmental chemicals and postpubertal breast composition in a Latino cohort

Investigator from Max Delbrück Center for Molecular Medicine (HZ)

Enzymatic DNA deamination and the immunity/cancer balance

Melanoma of skin All cancers but non-melanoma skin cancer

Bing Xu

Enzyme-instructed self-assembly for molecular anticancer nanomedicines

Melanoma of skin All cancers but non-melanoma skin cancer

Allan Weissman

Enzymes and Substrates of the Ubiquitin Conjugating System

All cancers but non-melanoma skin cancer

Mark Udey

EpCAM (CD326) Function in Epithelial Cell Biology and Immunophysiology

All cancers but non-melanoma skin cancer

Bingcheng Wang

EphA2 kinase in prostate cancer

Dezheng Huo

Epidemiological Study of Breast Cancer in Uganda and Cameroon

Mary Anne Rossing

Epidemiologic factors and survival by molecular subtypes of ovarian cancer

Maxwell Kligerman

Epidemiology of Oral HPV induced Head and Neck Cancer in Haiti

Other pharynx Lip, oral cavity Larynx

Investigator from Heinrich Heine University Düsseldorf

Epidermal growth factor receptor (EGFR) activation by cytohesins - Structural Insights

Melanoma of skin All cancers but non-melanoma skin cancer

Jayson Xiao Chen

Epigenetic changes in a PhIP-induced prostate cancer model in hCYP1A mice

Rita Rebollo Figueiredo Da Sil

Epigenetic deregulation of transposable elements contributes to Hodgkin lymphoma microenvironment formation

Hodgkin lymphoma

Birgit Knoechel

Epigenetic mechanisms of drug resistance in T-cell acute lymphoblastic leukemia

Xifeng Wu

Epigenetic miRNA, SNP Signatures, and their Functions in Lung Cancer Outcomes

Trachea, bronchus and lung

Ah-Ng Tony Kong

Epigenetic modifications by dietary PEITC in prostate cancer

Pamela Hoodless

Epigenetic Modifications Regulating Hepatocellular Carcinoma and Hepatocyte Differentiation

Liver and intrahepatic bile ducts

Keisuke Ito

Epigenetic regulation by microRNA of MDS pathogenesis

Hematology and hematologic malignancies

Shalini Oberdoerffer

Epigenetic Regulation of Alternative Pre-mRNA Splicing

All cancers but non-melanoma skin cancer

Vladimir A Botchkarev

Epigenetic regulation of skin development and keratinocyte differentiation

Melanoma of skin Non-Melanoma skin cancer

Paul Khavari

Epigenetic Regulators in Tumor Progression

Non-Melanoma skin cancer

Martin Allday

Epigenetic reprogramming of B cells in viral persistence, disease pathogenesis and tumour immunosurveillance.

Melanoma of skin All cancers but non-melanoma skin cancer

Michael A Dyer

Epigenetic Reprogramming of Retinal Neurons

Brain, nervous system

Kunal Rai

Epigenetics of Melanoma Metastasis

Melanoma of skin

Kenneth W Gross

(Epi)Genomic Drivers of Primary and Metastatic Pancreatic Islet Cell Carcinoma

Jeffrey J Fredberg

Epithelial layer jamming in breast cancer cell migration

Scott E Evans

Epithelial mechanisms of inducible resistance to AML-associated pneumonia

Philip A Beachy

Epithelial/stromal signaling in bladder and prostate cell proliferation

Prostate Bladder

Elliott D Kieff

Epstein-Barr Virus LMP1-Mediated Oncogenecity

Hodgkin lymphoma

Elliott D Kieff

Epstein-Barr Virus Nuclear Protein in B Cell Growth Transformation

Non-Hodgkin lymphoma Hodgkin lymphoma

Swathi Arur

Erk-mediated regulation of Dicer and Drosha function in C. elegans

Melanoma of skin All cancers but non-melanoma skin cancer

Fenggang Yu

Establishment of Epstein-Barr Virus Infection ex vivo Models in Healthy and Pre-Malignant Nasopharyngeal Epithelial Cell Cultures

Serigne Magueye

Ethnic Difference in Prostate Cancer

David Hammond

Evaluating the Impact of Mandatory Nutrition Information on Menus

All cancers but non-melanoma skin cancer

Pediatric oncology or childhood cancer

Kurt Straif

Evaluation of Carcinogenic Risks to Humans

Trachea, bronchus and lung Bladder

Ritu Aneja

Evaluation of centrosome amplification as a risk-predictor for breast cancer aggr

Brid Ryan

Examining Novel Roles of Nicotine and Tobacco Smoke on RNA Biology

Trachea, bronchus and lung

Brid Ryan

Examining the Inverse Relationship Between Parkinson's Disease and Lung Cancer

Trachea, bronchus and lung

Eric Daniel Olmon

Examining the Kinetics of Base Excision Repair in the Context of Chromatin

Melanoma of skin All cancers but non-melanoma skin cancer

Simon D Spivack

Exhaled microRNAs leveraged for lung cancer risk assessment

Trachea, bronchus and lung

Song Yao

Exome Array Analysis of Reproductive Aging and Breast Cancer in African Americans

Douglas Stewart

Exome-sequencing of neurofibromatosis type 1-associated atypical neurofibromas

Brain, nervous system

David C Lyden

Exosome-Mediated Transfer of c-MET to Bone Marrow Progenitors Promotes Metastasis

Melanoma of skin

Nelson Chao

Expanding cancer care in the lake region of Tanzania

All cancers but non-melanoma skin cancer

Stephen Scwartz

EXPANDING SEER TO INCLUDE MOLECULAR PROFILING IN NON-SMALL CELL LUNG CANCER (NSCLC)

Trachea, bronchus and lung

Bert W O'Malley

Expansion of NURSA Transcriptomine Annotation

Melanoma of skin All cancers but non-melanoma skin cancer

Paul R Jensen

Exploiting Microbial Diversity for Natural Product Discovery

All cancers but non-melanoma skin cancer

Clinton Kylie Matson

Exploiting the Genomic Programs Underlying AR-Independent Prostate Cancer

Mark E Hay

Exploration, Conservation, and Development of Marine Biodiversity in Fiji and the Solomon Islands

All cancers but non-melanoma skin cancer

Darren Richard Carpizo

Exploration of a Mutant p53 Reactivating Compound

Rahul Nene

Exploration of Genome Stability as a Therapeutic Target in Cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Keisuke Nagao

Exploring Mechanisms that Govern Immune Homeostasis in Skin

Non-Hodgkin lymphoma

Hematology and hematologic malignancies Pathology

Marco Marra

Exploring the relationship between the genome and the epigenome in cancers

Melanoma of skin All cancers but non-melanoma skin cancer

Stuart Keith Calderwood

Extracellular Hsp70 and hyperthermia in tumor therapy

James Phang

Extracellular Matrix and Stress Substrates: the Role of Prolidase

All cancers but non-melanoma skin cancer

Hugh S. Gannon

Extraordinary responder cell lines reveal unique targetable genetic dependencies

Investigator from French National Centre for Scientific Research (CNRS)

Fanconi anemia: a disease model to understand causes and consequences of common fragile site instability

Melanoma of skin All cancers but non-melanoma skin cancer

Junjie Chen

Fanconi anemia pathway in DNA damage repair

Melanoma of skin All cancers but non-melanoma skin cancer

Madeline Parsons

Fascin-dependent control of nuclear plasticity in invading cells

Melanoma of skin All cancers but non-melanoma skin cancer

Forest M White

FASEB SRC on Protein Kinases, Cellular Plasticity and Signal Rewiring

All cancers but non-melanoma skin cancer

Marcus E Peter

Fas protects cancer stem cells from death

William B Kinlaw

Fatty Acids and Cancer

Tony E. Godfrey

Feasibility of Molecular Cytology for the Management of Barretts Esophagus

Elizabeta Nemeth

Ferroportin Structure and function

Melanoma of skin All cancers but non-melanoma skin cancer

Dipak Kumar Sarkar

Fetal alcohol, estrogen-regulated genes and prostate cancer

Chu Chen

FFPE Validation of a Survival Gene Signature in HPV-Negative Oral Cavity Cancer

Stomach Lip, oral cavity

Radiation Oncology

William G Cance

Focal Adhesion Kinase - Tumor Biology and Therapeutics

Pancreas Breast

S Perwez Hussain

Forkhead-box (FOX) Transcription Factors in the Progression of Pancreatic Cancer

Anatoly Zhitkovich

Formaldehyde Genotoxicity

Melanoma of skin All cancers but non-melanoma skin cancer

Andrew E Aplin

FOXD3 up-regulation and ERBB3 signaling as an adaptive response to RAF inhibitors

Melanoma of skin

Andrew E Aplin

FOXD3 Up-Regulation and ERBB3 Signaling as an Adaptive Response to RAF Inhibitors

Melanoma of skin

Eran Segal

From DNA sequence to expression: A quantitative approach from yeast to human

Melanoma of skin All cancers but non-melanoma skin cancer

Eran Segal

From DNA Sequence to Expression: a Quantitative Approach from Yeast to Human

All cancers but non-melanoma skin cancer

Beatriz M Champagne

From Production to Retailing: Policy-Oriented Research on Tobacco Economy in Argentina

All cancers but non-melanoma skin cancer

Patrick G Harran

Fully Synthetic Prodiginines as Probes of Protein-Protein Interactions Regulating

All cancers but non-melanoma skin cancer

Radiation Oncology

Wenyi Wei

Functional analysis of beta-TRCP in cell cycle control and DNA damage response

Melanoma of skin All cancers but non-melanoma skin cancer

Shyam Sharan

Functional Analysis of Breast Cancer Susceptibility Genes in Mice

Lawrence J Marnett

Functional Analysis of Cyclooxygenase-2

Charles J Dimitroff

Functional Analysis of Galectin-1 Ligands in Melanoma Progression

Melanoma of skin

Shyam Sharan

Functional Analysis of Human Breast Cancer Susceptibility Gene Variants

Charles G Mullighan

Functional analysis of leukemic CREBBP mutations

Pediatric oncology or childhood cancer

Calvin J Kuo

Functional Analysis of Oncogenic Networks in Primary Organoids

Melanoma of skin All cancers but non-melanoma skin cancer

Alvaro Monteiro

Functional Analysis of Ovarian Cancer GWAS Loci

Teru Hideshima

Functional and biologic significance of deacetylase3 inhibition in myeloma

Multiple myeloma and immunoproliferative diseases

Ann Mullally

Functional and Molecular Dissection of Myeloproliferative Neoplasm Stem Cells

Dario Marchetti

Functional characterization of brain-colonizing breast cancer CTC subsets

Philip A Hieter

Functional Determinants of Chromosome Segregation

All cancers but non-melanoma skin cancer

Julio A Aguirre-Ghiso

Functional Determinants of Metastatic Dormancy

Other pharynx Nasopharynx

Paul Meltzer

Functional Genomics of Sarcoma

Luc Gordon Trang Morris

Functionalizing recurrent FAT1 mutations and deletions in oral cancer

Lip, oral cavity

Donald W. Kufe

Functional role of the MUC1-C oncoprotein in non-small cell lung cancer

Trachea, bronchus and lung

James Woodgett

Functional roles of glycogen synthase kinase-3 in cellular regulation and cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Michael Ryan Corces-Zimmerman

Functional significance of Pre-Leukemic HSC in Human Acute Myeloid Leukemia

Keping Xie

Functional Validation of Pancreatic Cancer Progression Biomarker

Neil Osheroff

Function and Biology of Eukaryotic DNA Topoisomerases

Kun P Lu

Function and Regulation of the Phosphorylation-Specific Prolyl Isomerase Pin1

Robert G Roeder

Function and targeting of a stable transcription factor complex in leukemia

Dimitar B Nikolov

Function-blocking anti-ADAM protease antibodies for inhibition of tumorigenesis - NY

Non-Hodgkin lymphoma Hodgkin lymphoma Breast

Xuebiao Yao

Function of ACAP4 in CCL18-Stimulated Breast Cancer Metastasis

David M. Briscoe

Function of DepTOR in T Cell Activation and Alloimmunity

Melanoma of skin All cancers but non-melanoma skin cancer

Ashish Lal

Function of Mutant p53-regulated microRNAs in Cancer Cells

Colorectum All cancers but non-melanoma skin cancer

John J Wysolmerski

Function of the Calcium Sensing Receptor in the Breast

Joseph Ziegelbauer

Functions of KSHV microRNAs

Sharon Y. R. Dent

Functions of Mammalian Histone Modifiers

Melanoma of skin All cancers but non-melanoma skin cancer

Marc Nicklaus

Fundamentals of Ligand-Protein Interactions

All cancers but non-melanoma skin cancer

Marc Nicklaus

Fundamentals Of Ligand-Protein Interactions

All cancers but non-melanoma skin cancer

Marc Nicklaus

Fundamentals of Ligand-Protein Interactions – Rockville

All cancers but non-melanoma skin cancer

Michelle Brazas

Gaining informatics skills to support translational cancer research: Canadian Bioinformatics Workshop on Cancer Genomics 2014

Melanoma of skin All cancers but non-melanoma skin cancer

Cassian Yee

Gastric Cancer Immunity and Immunotherapy

Jason Mills

Gastric Cancer in Nicaragua

Garth Powis

Gastric Cancer Sequencing

Xue Sean Li

Gender Difference in Bladder Cancer Susceptibility

Zhi-Ming Zheng

Gene Expression and Post-Transcriptional Regulation of DNA Tumor Viruses

Jill P. Mesirov

GenePattern Notebooks for Cancer Research

Melanoma of skin All cancers but non-melanoma skin cancer

Investigator from Humanitas Research Hospital

Generation and maintenance of long-lived memory T cells in humans

Melanoma of skin All cancers but non-melanoma skin cancer

Naoto Hirano

Generation of Highly Avid Anti-Tumor CTL for Optimal Adoptive Immunotherapy

All cancers but non-melanoma skin cancer

Investigator from VU University Amsterdam

Generation of safe and efficient, off-the-shelf, chimeric antigen receptor (CAR)-engineered T cells for broad application

Multiple myeloma and immunoproliferative diseases

Charles Vinson

Gene Regulation and Function: The B-ZIP Proteins

All cancers but non-melanoma skin cancer

Charles Vinson

Gene Regulation and Function: The B-ZIP Proteins – Rockville

All cancers but non-melanoma skin cancer

Takeshi Egawa

GENE REGULATION GOVERNING T LYMPHOCYTE FATE DECISIONS

Jason Mills

Genes that Regulate onset of Metaplasia in the Stomach

Eric Asselin

Gene therapy of chemoresistant and metastatic cancers (CANADA RESEARCH CHAIRHOLDER)

Ovary Corpus uteri

Glenn Merlino

Genetically Engineered Mouse Models to Study RTK Function in Melanoma

Melanoma of skin

William M Sugden

Genetic Analysis of EBVs Immortalizing Genes

Non-Hodgkin lymphoma

Hematology and hematologic malignancies Pathology Pediatric oncology or childhood cancer

Remy Bosselut

Genetic Analysis of T-cell Differentiation

Remy Bosselut

Genetic Analysis of T-cell Differentiation – Rockville

Remy Bosselut

Genetic Analysis of T-cell Differentiation – Rockville

Michael C Ostrowski

Genetic Analysis of the Breast Tumor Microenvironment

Michael Gottesman

Genetic Analysis of the Multidrug Resistance Phenotype in Tumor Cells

Ovary Melanoma of skin Liver and intrahepatic bile ducts Leukaemia Brain, nervous system

Kenneth M Kaye

Genetic and Biochemical Studies of KSHV LANA

Jérôme Fortin

Genetic and functional dissection of PTEN tumor suppressor activity in high-grade ovarian serous carcinoma

Robert K Bradley

Genetic and molecular basis for SRSF2 mutations in myelodysplasia

Matthew D Ringel

Genetic and Signaling Pathways in Epithelial Thyroid Cancer

Leonid Raskin

Genetic Basis of Familial Colorectal Cancer Type X

Ronald Levy

Genetic Basis of Signaling Heterogeneity in Human Follicular Lymphoma

Non-Hodgkin lymphoma Hodgkin lymphoma

Peter Demant

Genetic components of adverse effects of cisplatin therapy

Melanoma of skin All cancers but non-melanoma skin cancer

Bingwei Lu

Genetic Control of Neural Stem Cell Homeostasis

Brain, nervous system

Iannis Aifantis

Genetic Dissection of Acute Myeloid Leukemia

Hematology and hematologic malignancies Pathology

Diane M Robins

Genetic Dissection of Context-Dependent and Opposing Roles of Androgen Receptor

Mary Ellen Conley

Genetic Etiology of Agammaglobulinemia with Absent B Cells

Non-Hodgkin lymphoma Leukaemia Hodgkin lymphoma

Alison Motsinger-Reif

Genetic Etiology of Cancer Drug Response

Hodgkin lymphoma Breast

Rameen Beroukhim

Genetic evolution of glioblastomas during radiation and temozolomide therapy

Brain, nervous system

Jeffrey Lee

Genetic Mechanisms of Immunity and Inflammation in Mmelanoma Progression

Melanoma of skin

Seth J Corey

Genetic Modifiers for Cancer Stem Cells in Secondary MDS/AML

Hematology and hematologic malignancies Pediatric oncology or childhood cancer

Kent Hunter

Genetic Modifiers of Initiation and Progression of Mammary Cancer

Toni Choueiri

Genetic Predictors of Response to mTOR inhibitors in advanced Renal Cancer

Kidney, renal pelvis and ureter

Ronald A Depinho

Genetics and Biology of Pancreatic Ductal Adenocarcinoma

Maxwell Lee

Genetics and Epigenetics of Cancer

Cheryl Winkler

Genetics of Complex Diseases and Health Disparities

Kidney, renal pelvis and ureter

Timothy R Rebbeck

Genetics of Prostate Cancer in Africa

Peng Wei

Genetic Susceptibility and Risk Model for Pancreatic Cancer

Matthew L. Meyerson

Genome Characterization Center (GCC)

Melanoma of skin All cancers but non-melanoma skin cancer

Randal S Tibbetts

Genome maintenance functions of CREB/ATF transcription factors

All cancers but non-melanoma skin cancer

Manal Metwally Hassan

Genome-Wide Association Study (GWAS) in Hepatocellular Carcinoma (HCC)

James D Mckay

Genomic and transcriptomic characterization of atypical carcinoids of the lung

Trachea, bronchus and lung

Kosj Yamoah

Genomic Biomarker for Aggressive Prostate Cancer in Men of African Descent

Snorri Thorgeirsson

Genomic Classification of Human Liver Cancer

Liver and intrahepatic bile ducts

Collaborator from Tel Aviv University

Genomic diagnostics beyond the sequence

Melanoma of skin All cancers but non-melanoma skin cancer

Peter S Hammerman

Genomic Discovery and Targeted Therapeutics in Squamous Cell Lung Cancer

Trachea, bronchus and lung

David L Woodland

Genomic Instability and DNA Repair

All cancers but non-melanoma skin cancer

Harry Ostrer

Genomics and Predictive Modeling of Prostate Cancer Heath Disparity

Miriam Poirier

Genotoxicity and mitochondrial toxicity of antiretroviral NRTI and PI drugs

All cancers but non-melanoma skin cancer

Anatoly Zhitkovich

Genotoxicity of Chromium Compounds

Melanoma of skin All cancers but non-melanoma skin cancer

Hugo Aerts

Genotype and Imaging Phenotype Biomarkers in Lung Cancer

Trachea, bronchus and lung

Frank Furnari

Genotypic Interactions in Brain Cancer Heterogeneity

Brain, nervous system

Michele Carbone

Germline BAP1 Mutations and Malignant Mesothelioma: Mechanisms and Early Detection

Trachea, bronchus and lung

Zsofia Kinga Stadler

Germline Susceptibility in Double Primary Cancers via Nexy-Generation Sequencing

Melanoma of skin All cancers but non-melanoma skin cancer

Susan E Erdman

GI Tract Dysbiosis and Breast Cancer

Anne-Claude Gingras

Global approaches to unravel PP2A function

Melanoma of skin All cancers but non-melanoma skin cancer

Ming Tan

Glucose Metabolism and ErbB2-Mediated Cancer Progression

Radoslav Goldman

Glycans in Hepatocellular Carcinoma

Raja Mazumder

GlycoCentral: Glycobiology data and tool integration with genes, proteins and lipids

Melanoma of skin All cancers but non-melanoma skin cancer

Xiaofeng Steven Zheng

Growth Control and Anti-Cancer Drug Mechanisms

Melanoma of skin All cancers but non-melanoma skin cancer

Alan Perantoni

Growth/Differentiation Factors in Organogenesis

All cancers but non-melanoma skin cancer

Mien-Chie Hung

Growth Factor Receptor in Breast Cancer Progression and Metabolic Regulation

Kenneth D Irvine

Growth regulation by the Fat signaling pathway

Melanoma of skin All cancers but non-melanoma skin cancer

Anna Bianchi-Smiraglia

GTP Metabolism Controls Tumor Invasion

Melanoma of skin

James Versalovic

Gut L-Histidine Metabolism and Histamine Signaling in Colonic Neoplasia

Johanna W Lampe

Gut Microbiota and colonic gene expression: A ligran trial in humans

Wendy S. Garrett

Gut microbiota and inflammatory monocytes in colorectal cancer

Jennifer L Guerriero

Harnessing anti-tumor macrophages for cancer therapy

Melanoma of skin All cancers but non-melanoma skin cancer

Uwe Rix

Harnessing beneficial off-target effects of kinase inhibitors in lung cancer

Trachea, bronchus and lung

Amy R. Howell

Harnessing NKT Cell Activation by Glycolipids

Melanoma of skin All cancers but non-melanoma skin cancer

Wei Gu

HAUSP inhibitors in p53-wild type and p53-mutant tumors

Non-Hodgkin lymphoma Multiple myeloma and immunoproliferative diseases Colorectum

John Tavis

HBV Drug Development

Liver and intrahepatic bile ducts

J H James Ou

HBV Replication and Carcinogenesis

Liver and intrahepatic bile ducts

Ya-Huei Kuo

HDAC8 Mediated Regulation of Acute Myeloid Leukemia Pathogenesis and Maintenance

Hematology and hematologic malignancies Pathology

Marilyn D Resh

Hedgehog Acyltransferase as a target in cancer

Mien-Chie Hung

Hedgehog Pathways and Tumor Initiating Cells in Esophagus Cancer

Elaine Jaffe

Hematopathology Diagnosis

Hodgkin lymphoma

Hematology and hematologic malignancies Pathology

Andre Michael Lieber

Hematopoietic stem cell based gene therapy of breast cancer

Dario Marchetti

Heparanase Mechanisms in Brain-metastatic Breast Cancer

Ralph D Sanderson

Heparanase Regulation of Myeloma Metastasis: Mechanism and Therapy

Multiple myeloma and immunoproliferative diseases

Hematology and hematologic malignancies

Ningling Kang

Hepatic Stellate Cell Regulation of Metastatic Growth in the Liver

Liver and intrahepatic bile ducts

Robert F Schwabe

Hepatic Stellate Cells and Liver Cancer

Liver and intrahepatic bile ducts

Nancy Joan Raab-Traub

Herpesviral, Oncogenesis, Latency and Reactivation

Non-Hodgkin lymphoma Kaposi sarcoma Cervix uteri

S Diane Hayward

Herpesvirus Protein Kinases: Substrate Recognition and Pathway Targeting

Nasopharynx Hodgkin lymphoma

Thomas Hudson

High resolution genetic analysis of genetic loci implicated in colorectal cancer

Stuart Le Grice

High-Resolution Protein and Nucleic Acid Footprinting

All cancers but non-melanoma skin cancer

Dmitri Petrov

High-resolution study of adaptation in haploid and diploid populations of yeast

Melanoma of skin All cancers but non-melanoma skin cancer

Inanc Birol

High throughput analysis of RNA-seq reads to characterize alternative polyadenylation in myeloid malignancy

Peter J Burke

High-throughput on-chip platform for interrogation of mitochondrial membrane potential and apoptosis

All cancers but non-melanoma skin cancer

Harlan S. Robins

High-throughput sequencing of the T cell receptor in colorectal tumor infilt

Chad Daniel Huff

High-throughput sequencing to identify novel melanoma susceptibility genes

Melanoma of skin

Ju-Seog Lee

Hippo Pathway in Hepatocellualr Carcinoma

Liver and intrahepatic bile ducts

Fernando Camargo

Hippo signaling and the control of epidermal development and growth

Melanoma of skin All cancers but non-melanoma skin cancer

Jianmin Zhang

Hippo signaling pathway in breast cancer disparities: a translational approach

Maria V Panchenko

Histone Acetyl Transferase HBO1 in kidney epithelial cell cycle

Melanoma of skin All cancers but non-melanoma skin cancer

Yang Shi

Histone demethylases and regulation of chromatin and transcription in eukaryotes

Melanoma of skin All cancers but non-melanoma skin cancer

Brendan D Price

Histone methylation controls activation of ATM and the radiation response

Melanoma of skin All cancers but non-melanoma skin cancer

Radiation Oncology

Frank Maldarelli

HIV-1 Genetic Variation in Infected Individuals

All cancers but non-melanoma skin cancer

Stuart Le Grice

HIV-1 RNase H as a Therapeutic Target

All cancers but non-melanoma skin cancer

Marc Nicklaus

HIV Integrase Modeling and Computer-Aided Inhibitor and Microbicide Development

All cancers but non-melanoma skin cancer

Sriram Subramaniam

HIV Neutralization and Mechanisms of Cellular Entry

All cancers but non-melanoma skin cancer

Frank Maldarelli

HIV Persistence During Suppressive Antiretroviral Therapy

All cancers but non-melanoma skin cancer

Paul Khavari

Homeostatic Regulators Disrupted in Skin Carcinogenesis

Melanoma of skin Non-Melanoma skin cancer

Maria Jasin

HOMOLOGY-DIRECTED DNA REPAIR PROTEINS BRCA2 AND RAD51 IN TUMOR RELEVANT TISSUES

Li Yang

Host immature myeloid cells in tumor suppressor or promoter roles of TGFbeta

All cancers but non-melanoma skin cancer

Conor C Lynch

Host MMP-Mediated Regulation of the Vicious Cycle of Prostate to Bone Metastases

Micah A Luftig

Host Pathways Regulating Epstein-Barr Virus-Mediated B Cell Growth Transformation

Non-Hodgkin lymphoma

Hematology and hematologic malignancies Pathology

Prashant Desai

How Does KSHV Small Capsid Protein Function to Promote Self-Assembly?

Matthew L. Meyerson

How do genome alterations cause human lung cancer?

Trachea, bronchus and lung

John Diffley

How the eukaryotic replicative DNA helicase is loaded and activated

Melanoma of skin All cancers but non-melanoma skin cancer

Susan Mackem

Hoxd and Gli3-Hoxd interaction roles in Hedgehog regulated digit morphogenesis

All cancers but non-melanoma skin cancer

Laimonis A Laimins

HPV and the DNA Damage Response

Tsetsegsaikhan Batmunkh

HPV detection rates in young women 4 years following the 4-valent HPV vaccine in Mongolia

Richard M Peek

H. Pylori Relationship to Digestive Diseases and Cancer

Irving L. Weissman

HSC Diversity, in aging, ontogeny, and transformation

Dhyan Chandra

Hsp60 regulation of apoptosis in prostate cancer

Christophe P Nicot

HTLV-I Tax induces DNA Breaks and Inhibits HR Repair through Activation of NF-kB

Hematology and hematologic malignancies Pathology

Vladimir Larionov

Human Artificial Chromosomes for Cancer Research and Functional Genomics

All cancers but non-melanoma skin cancer

Akil Hamza

Human complementation of yeast mutations to identify candidate cancer therapeutic targets

Melanoma of skin All cancers but non-melanoma skin cancer

Jeffrey Schlom

Human Immune Responses to Tumor Antigens for Cancer Vaccine Development

Trachea, bronchus and lung

Meenhard F Herlyn

Human Melanoma: Etiology, Progression and Therapy

Melanoma of skin

Meenhard F Herlyn

Human Melanoma: Etiology, Progression and Therapy

Melanoma of skin

Dimiter Dimitrov

Human Monoclonal Antibodies Against Cancer

Brain, nervous system

Anne E Cress

Human Prostate Cancer Metastasis and Laminin Binding Integrins

Carl F Ware

HVEM-BTLA Pathway in Lymphoma

Non-Hodgkin lymphoma

Hematology and hematologic malignancies

Jiangbin Ye

Hypoxia induces SHMT2 to regulate cellular redox and epigenetics

Melanoma of skin All cancers but non-melanoma skin cancer

Guy S Salvesen

IAP Family Proteins and Cancer

Hematology and hematologic malignancies Pathology

Inanc Birol

Identification and annotation of 3' UTR ends using RNA-seq data

All cancers but non-melanoma skin cancer

Michael R Green

Identification and Characterization of Genes that Suppress BCR-ABL+ Leukemia

Hematology and hematologic malignancies Pathology

Thomas Ried

Identification and Functional Characterization of Colorectal Cancer Genes

Charles M. Rudin

Identification and validation of synthetic lethality in KRAS mutant lung adenocarcinoma patient derived xenografts

Trachea, bronchus and lung

Collin Melton

Identification, Characterization, and Prediction of Cancer Driver Mutations in Regulatory Regions

Melanoma of skin All cancers but non-melanoma skin cancer

Hui-Kuan Lin

Identification of a new strategy for cancer therapy

Melanoma of skin All cancers but non-melanoma skin cancer

Shing Zhan

Identification of drivers of metastasis in Ewing sarcoma using next-generation sequencing technologies

Javed Khan

Identification of Genes for Predicting Prognosis in Pediatric Cancers

All cancers but non-melanoma skin cancer

Pediatric oncology or childhood cancer

Cheryl Winkler

Identification of Genetic Factors Associated with Infectious Diseases

Liver and intrahepatic bile ducts

Shyam Sharan

Identification of Genetic Interactors of Brca2

Damien Garbett

Identification of mechanisms involved in coordinated group migration

Melanoma of skin All cancers but non-melanoma skin cancer

Eileen P. White

Identification of Metabolic Vulnerabilities of Ras-Driven Cancer Cells

Melanoma of skin All cancers but non-melanoma skin cancer

Yuzhuo Wang

Identification of miRNAs and their Specific Gene Targets that are Critical for Prostate Cancer Metastases

Hanyang Lin

Identification of new microRNA biomarkers and candidate target genes in primitive CML cells using global comparative RNA analyses

Javed Khan

Identification of Novel Mutations In Pediatric Cancers

Sarcoma All cancers but non-melanoma skin cancer

Pediatric oncology or childhood cancer

Shun-Cheng Li

Identification of protein-protein interactions and the resultant signaling networks (CANADA RESEARCH CHAIRHOLDER)

Melanoma of skin All cancers but non-melanoma skin cancer

James M Olson

Identification of Small Molecule Inhibitors of PHF5A for Glioblastoma

Brain, nervous system

Channing J Der

Identification of synthetic lethal interactors in pancreatic cancer

John Dick

Identify and understand the differences between normal HSCs and LSCs (CANADA RESEARCH CHAIRHOLDER)

William Mallory Grady

Identify and validate novel epigenetic molecular markers for colorectal neoplasm

Neil Johnson

Identifying BRCA1 protein variants that provide resistance to therapy

Bruce E Clurman

Identifying CDK4 and CDK6 substrates in cancers and cancer therapy

Melanoma of skin All cancers but non-melanoma skin cancer

Marcel Bally

Identifying Cytoprotective Responses Triggered Following Initial Exposure to Targeted Therapy: Defining Improved Treatment Strategies for Patients with HER-2 Positive Breast Cancer

Thomas Ried

Identifying Diagnostic Markers for Cervical, Breast, and Prostate Cancer

Alex Toker

Identifying lincRNAs that Mediate PI 3 Kinase Dependent Breast Cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Investigator from University of Groningen

Identifying pathways of cellular nanoparticle uptake and early processing for novel nanomedicine applications

Melanoma of skin All cancers but non-melanoma skin cancer

William Isaacs

Identifying Prostate Cancer Genes

Elsa Beyer Krall

Identifying STAT3 Co-dependencies in Cancer

Melanoma of skin All cancers but non-melanoma skin cancer

Javier Di Noia

Identifying the function and regulation of proteins that are part of the mechanisms mutating the antibody genes (CANADA RESEARCH CHAIRHOLDER)

Melanoma of skin All cancers but non-melanoma skin cancer

Ewan Smith

Identifying the molecular targets of inhibitors of androgen receptor mediated transcription by photoaffinity labelling

Melanoma of skin All cancers but non-melanoma skin cancer

William Figg

Identify SNPs and Polymorphisms Involved in the Development of Prostate Cancer

Zhe Li

IGF/IGF1R signaling in hematopoiesis and leukemogenesis

Nader Rahimi

IGPR-1 in colon cancer chemotherapy

Jin Q Cheng

IKBKE/IKKE (epsilon) Kinase in Non-small Cell Lung Cancer

Trachea, bronchus and lung

Michael Karin

IKK <alpha> and the Control of Prostate Cancer Metastasis

Marcel R M Van Den Brink

IL-22 in Thymic Regeneration

Thomas Waldmann

IL-2/IL-15 Cytokine Receptor: Implications for Cancer Therapy and Vaccine Design

Hematology and hematologic malignancies Pathology

Bin Tian

Illumina NextSeq500 DNA Sequencing System

Melanoma of skin All cancers but non-melanoma skin cancer

Bjoern Markus Reinhard

Illuminating Dynamic Receptor Clustering in the Epidermal Growth Factor Receptor

Melanoma of skin All cancers but non-melanoma skin cancer

Tudor Oprea

Illuminating the Druggable Genome

All cancers but non-melanoma skin cancer

Clare M Tempany

Image Guided Therapy Center

Prostate Brain, nervous system

Anirban Maitra

Imaging and Molecular Correlates of Progression in Cystic Neoplasms of the Pancreas

Daniel M Spielman

Imaging Brain Metabolism Using MRS of Hyperpolarized 13C-Pyruvate

Brain, nervous system

Sriram Subramaniam

Imaging Cellular Assemblies With Three-Dimensional Electron Microscopy

All cancers but non-melanoma skin cancer

Paul Tempst

Immobilized protease activity tests for developing functional cancer biomarkers.

David L Woodland

Immune Evolution in Cancer

Non-Hodgkin lymphoma Multiple myeloma and immunoproliferative diseases

Hematology and hematologic malignancies Pathology

Jung-Hyun Park

Immune Regulatory Roles of Suppressor Of Cytokine Signaling (SOCS) Molecules

All cancers but non-melanoma skin cancer

Tim Greten

Immune Suppressor Mechanism Analysis in Patients with Hepatocellular Carcinoma

Liver and intrahepatic bile ducts

Tim Greten

Immune Suppressor Mechanism in a Murine Model of Hepatitis and Liver Cancer

Liver and intrahepatic bile ducts

Tim Greten

Immune suppressor mechanisms in patients with GI cancer

Stomach Oesophagus Lip, oral cavity Colorectum

Crystal Mackall

Immunobiology and Immunotherapy of Pediatric Cancer

Sarcoma Trachea, bronchus and lung Leukaemia

Pediatric oncology or childhood cancer

Elizabeth Mittendorf

Immunologic Aspects of Triple Negative Breast Cancer and the Effects of Neoadjuvant Systemic Therapy

Hans Schreiber

Immunology of Unique Tumor Specific Antigens

Trachea, bronchus and lung Prostate Pancreas Ovary Colorectum Breast

Robert Wiltrout

Immunophysiological Mechanisms in the Biological Therapy of Cancer

All cancers but non-melanoma skin cancer

Brent Williams

Immunotherapy of leukemic stem cells

Ira Pastan

Immunotoxin Therapy of Solid and Hematopoietic Tumors: Preclinical Studies

All cancers but non-melanoma skin cancer

Hematology and hematologic malignancies Pathology

Richard G Pestell

Impact of Cyclin D1 Isoforms in Breast Cancer

Justin Sonnenburg

Impact of Diet on Intestinal Microbiota-Host Dynamics

Tamara Dubowitz

Impact of Greenspace Improvement on Physical Activity in a Low Income Community

All cancers but non-melanoma skin cancer

Ann M Moormann

Impact of Malaria on Shaping Immunity to EBV in the Etiology of Burkitt lymphoma

Non-Hodgkin lymphoma

Hematology and hematologic malignancies Pathology Pediatric oncology or childhood cancer

Mark D Adams

Impact of Mitochondrial Genome Variation on Extreme Prostate Cancer Disparities

Theodore Brown

Impact of VEPH1 on cancer associated signaling pathways in the promotion of ovarian cancer

Kevin Brown Chandler

Impaired Glycosylation of Vascular Endothelial Growth Factor Receptor 2 in Tumor Angiogenesis

Melanoma of skin All cancers but non-melanoma skin cancer

Sadhan Majumder

Implications of a novel glioblastoma classification defined by miR-21-Sox2 status

Brain, nervous system

Alexandre Orthwein

Importance of cyclin D1-USP11 interaction for the homologous repair pathway

Melanoma of skin All cancers but non-melanoma skin cancer

Gajanana Datta

Improved metabolic imaging using hyperpolarized 13C MR substrates

Melanoma of skin All cancers but non-melanoma skin cancer

Elizabeth J Shpall

IMPROVING CORD BLOOD TRANSPLANTATION

Pediatric oncology or childhood cancer

Kenneth Harder

Improving understanding of phagocyte biochemistry (CANADA RESEARCH CHAIRHOLDER)

Colorectum Breast

Fredrick R Schumacher

Imputation-Based Approach to Identify Low Frequency Variants in Prostate Cancer

Sharon E. Plon

Incorporation of Genomic Sequencing into Pediatric Cancer Care

Melanoma of skin All cancers but non-melanoma skin cancer

Pediatric oncology or childhood cancer

Patrick J. Loehrer

Indiana University Melvin and Bren Simon Cancer Center Support Grant

Melanoma of skin All cancers but non-melanoma skin cancer

Palliative Care

E. Antonio Chiocca

Indirubins: novel anti-invasive and anti-angiogenic drugs for malignant gliomas

Brain, nervous system

Alan Anderson

Inducible metabolism of xenochemicals and endogenous toxic compounds: Nuclear receptors and the CYP2B paradigm

Melanoma of skin All cancers but non-melanoma skin cancer

Carol A Lange

Inducible PTK6 expression drives oncogenic signaling in breast cancer

Tyshia Kyree Gwin

Induction of tumor suppressor p16INK4A by human papillomavirus 16 E7 oncoprotein

Trachea, bronchus and lung Other pharynx Oesophagus Non-Hodgkin lymphoma Nasopharynx Liver and intrahepatic bile ducts Kidney, renal pelvis and ureter Kaposi sarcoma Hodgkin lymphoma Colorectum Cervix uteri

David L Woodland

Inflammation, Infection and Cancer

All cancers but non-melanoma skin cancer

Guojun Li

Inflammatory Response miRNAs Predict HPV-associated Oropharyngeal Cancer Outcome

Ji-Yong Julie Kim

Influence of AKT pathway on progesterone receptor function in endometrial cancer

Elad Ziv

Influence of germ line genetic variation on myeloma progression and survival

Multiple myeloma and immunoproliferative diseases

Hematology and hematologic malignancies Pathology

Kevin Hasegawa Eng

Informatic Methods for Differential Signaling and Immune Co-Regulatory Expression

Andrew H Beck

INFORMATICS METHODS AND MODELS FOR COMPUTATIONAL PATHOLOGY

Melanoma of skin All cancers but non-melanoma skin cancer

Roman Perez-Soler

Inhaled DNA demethylating therapy for lung cancer and bronchial premalignancy

Trachea, bronchus and lung

Aaron David Schimmer

Inhibiting oncogenic kinases to target metabolism in AML

Jaffer A Ajani

Inhibition of Hedgehog Signaling in Gli-1+Adeno CA of the Esoph or GE junction

Eric Freed

Inhibition of HIV-1 Maturation

All cancers but non-melanoma skin cancer

David L. Ban

Inhibition of Oncogenic MdmX by Targeting its Motion

Brain, nervous system

Pediatric oncology or childhood cancer

Michael J Eck

Inhibitor-sensitive and -resistant EGFR mutants from lung cancer and glioblastoma

Trachea, bronchus and lung Brain, nervous system

Thomas A Gerken

Initiation and regulation of mucin-type O-glycosylation

Melanoma of skin All cancers but non-melanoma skin cancer

Mirit Aladjem

Initiation of DNA Replication in Mammalian Cells

All cancers but non-melanoma skin cancer

Marc Nicklaus

In Silico Screening for Cancer Targets

Trachea, bronchus and lung Leukaemia

Hematology and hematologic malignancies Pathology

Zelig Eshhar

In situ Redirection of T cell Specificity and Imaging of Targeted CAR Expression.

Melanoma of skin All cancers but non-melanoma skin cancer

Show more